CEA Rabbit Polyclonal Antibody

CEA
CEA (polyclonal) on colon.

CEA Rabbit Polyclonal Antibody

Specialties: Anatomic Pathology

Updated: 2018-01-11 08:59:58

Anti-CEA is employed essentially as a tool to assist in the distinction between adenocarcinoma and epithelioid malignant mesotheliomas,1 along with other markers such as those against calretinin, CK 5&6, CD15, HBME-1, MOC-31, and Ber-EP4.1 Another suggested use of anti-CEA is to immunophenotype various metastatic adenocarcinomas as a means of identifying their origin within a panel of different markers.1 Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.2,3 Polyclonal anti-CEA is useful in staining hepatocellular carcinoma in a canalicular pattern.2,4

  1. Shield PW, et al. Immunocytochemical staining of cytologic specimens. How helpful is it? Am J Clin Pathol. 1996; 105:157-62.
  2. Sheahan K, et al. Differential reactivities of carcinoembryonic antigen (CEA) and CEA-related monoclonal and polyclonal antibodies in common epithelial malignancies. Am J Clin Pathol. 1990; 94:157-64.
  3. Alkushi A, et al. Immunoprofile of cervical and endometrial adenocarcinomas using a tissue microarray. Virchows Arch. 2003; 442:271-7.
  4. Morrison C, et al. A comparison of CD10 to pCEA, MOC-31, and hepatocyte for the distinction of malignant tumors in the liver. Mod Pathol. 2002; 15:1279-87.

Specifications


  • Reactivity: paraffin
  • Control: Colon (Cytoplasmic)
  • Dilution Range: 1:200-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate236A-14
0.5 mL concentrate236A-15
1.0 mL concentrate236A-16
1.0 mL predilute ready-to-use236A-17
7.0 mL predilute ready-to-use236A-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate236A-14
0.5 mL concentrate236A-15
1.0 mL concentrate236A-16
1.0 mL predilute ready-to-use236A-17
7.0 mL predilute ready-to-use236A-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate236A-14
0.5 mL concentrate236A-15
1.0 mL concentrate236A-16
1.0 mL predilute ready-to-use236A-17
7.0 mL predilute ready-to-use236A-18

For research use only (RUO) in Japan

0.1 mL concentrate (RUO)236A-14-RUO
0.5 mL concentrate (RUO)236A-15-RUO
1.0 mL concentrate (RUO)236A-16-RUO
1.0 mL predilute ready-to-use (RUO)236A-17-RUO
7.0 mL predilute ready-to-use (RUO)236A-18-RUO

 

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