Cell Marque Portfolio

Hepatocyte Specific Antigen (Hep Par-1) (OCH1E5)

Mouse Monoclonal


Anti-hepatocyte specific antigen, also known as anti-Hep-Par1, recognizes both benign and malignant liver-derived tissues including such tumors as hepatoblastoma, hepatocellular carcinoma, and hepatic adenoma. It recognizes both normal adult and fetal liver tissue. The typical pattern is a granular cytoplasmic staining. This antibody is useful in differentiating hepatocellular carcinomas with adenoid features from adenocarcinomas, either primary in the liver or metastatic lesions to the liver. In labeling hepatoblastoma, it is useful in differentiating this entity from other small round cell tumors.

Specialties: Anatomic Pathology Gastrointestinal (GI) Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: liver
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1M/16min @ 37°C
  • Leica Bond
    Protocol F: ER2/30

References


  1. Minervini MI, et al. Mod Pathol. 1997; 10:686-692.
  2. Fasano M, et al. Mod Pathol. 1998; 11:934-938.
  3. Tsui WMS, et al. Am J Surg Pathol. 1999; 23:34-48.
  4. Wieczorek T, et al. Am J Clin Pathol. 2002; 118:911-21.
  5. Chu PG, et al. Am J Surg Pathol. 2002; 26:978-88.
  6. Maitra A, et al. Am J Clin Pathol. 2001; 115:689-94.

Last updated: 2017-05-24 08:46:09

Hepatocyte Specific Antigen (Hep Par-1)
Hepatocellular carcinoma shows a strong, diffuse and granular expression of hepatocyte specific antigen.

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Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: liver
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1M/16min @ 37°C
  • Leica Bond
    Protocol F: ER2/30

References


  1. Minervini MI, et al. Mod Pathol. 1997; 10:686-692.
  2. Fasano M, et al. Mod Pathol. 1998; 11:934-938.
  3. Tsui WMS, et al. Am J Surg Pathol. 1999; 23:34-48.
  4. Wieczorek T, et al. Am J Clin Pathol. 2002; 118:911-21.
  5. Chu PG, et al. Am J Surg Pathol. 2002; 26:978-88.
  6. Maitra A, et al. Am J Clin Pathol. 2001; 115:689-94.

Package Inserts

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Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate 264M-94
0.5 mL concentrate 264M-95
1 mL concentrate 264M-96
1 mL predilute 264M-97
7 mL predilute 264M-98
25 mL predilute 264M-90

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate 264M-94
0.5 mL concentrate 264M-95
1 mL concentrate 264M-96
1 mL predilute 264M-97
7 mL predilute 264M-98
25 mL predilute 264M-90

For in vitro diagnostic (IVD) use in the EU

0.1 mL concentrate 264M-94
0.5 mL concentrate 264M-95
1 mL concentrate 264M-96
1 mL predilute 264M-97
7 mL predilute 264M-98
25 mL predilute 264M-90

For research use only (RUO) in Japan

0.1 mL concentrate 264M-94-RUO
0.5 mL concentrate 264M-95-RUO
1 mL concentrate 264M-96-RUO
1 mL predilute 264M-97-RUO
7 mL predilute 264M-98-RUO
25 mL predilute 264M-90-RUO

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: liver
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1M/16min @ 37°C
  • Leica Bond
    Protocol F: ER2/30

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References


  1. Minervini MI, et al. Mod Pathol. 1997; 10:686-692.
  2. Fasano M, et al. Mod Pathol. 1998; 11:934-938.
  3. Tsui WMS, et al. Am J Surg Pathol. 1999; 23:34-48.
  4. Wieczorek T, et al. Am J Clin Pathol. 2002; 118:911-21.
  5. Chu PG, et al. Am J Surg Pathol. 2002; 26:978-88.
  6. Maitra A, et al. Am J Clin Pathol. 2001; 115:689-94.
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