Hepatocyte Specific Antigen (Hep Par-1) (OCH1E5) Mouse Monoclonal Antibody

Hepatocyte Specific Antigen (Hep Par-1)
Hepatocellular carcinoma shows a strong, diffuse and granular expression of hepatocyte specific antigen.

Hepatocyte Specific Antigen (Hep Par-1) (OCH1E5) Mouse Monoclonal Antibody

Specialties: Anatomic Pathology Gastrointestinal (GI) Pathology

Updated: 2018-01-31 11:36:38

Anti-hepatocyte specific antigen, also known as anti-Hep-Par1, recognizes both benign and malignant liver-derived tissues including such tumors as hepatocellular carcinoma. It recognizes both normal adult and fetal liver tissue. The typical pattern is a granular cytoplasmic staining. This antibody is useful in differentiating hepatocellular carcinomas with adenoid features from adenocarcinomas, either primary in the liver or metastatic lesions to the liver.1-6

  1. Minervini MI, et al. Utilization of hepatocyte-specific antibody in the immunocytochemical evaluation of liver tumors. Mod Pathol. 1997; 10:686-92.
  2. Chu PG, et al. Hepatocyte antigen as a marker of hepatocellular carcinoma: an immunohistochemical comparison to carcinoembryonic antigen, CD10, and alpha-fetoprotein. Am J Surg Pathol. 2002; 26:978-88.
  3. Wieczorek T, et al. Comparison of thyroid transcription factor-1 and hepatocyte antigen immunohistochemical analysis in the differential diagnosis of hepatocellular carcinoma, metastatic adenocarcinoma, renal cell carcinoma, and adrenal cortical carcinoma. Am J Clin Pathol. 2002; 118:911-21.
  4. Fasano M, et al. Immunohistochemical evaluation of hepatoblastomas with use of the hepatocyte-specific marker, hepatocyte paraffin 1, and the polyclonal anti-carcinoembryonic antigen. Mod Pathol. 1998; 11:934-8.
  5. Maitra A, et al. Immunoreactivity for hepatocyte paraffin 1 antibody in hepatoid adenocarcinomas of the gastrointestinal tract. Am J Clin Pathol. 2001; 115:689-94.

Specifications


  • Reactivity: paraffin
  • Control: Liver (Cytoplasmic)
  • Dilution Range: 1:100-1:500 *

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

25.0 mL predilute ready-to-use264M-90
0.1 mL concentrate264M-94
0.5 mL concentrate264M-95
1.0 mL concentrate264M-96
1.0 mL predilute ready-to-use264M-97
7.0 mL predilute ready-to-use264M-98

For in vitro diagnostic (IVD) use in Canada

25.0 mL predilute ready-to-use264M-90
0.1 mL concentrate264M-94
0.5 mL concentrate264M-95
1.0 mL concentrate264M-96
1.0 mL predilute ready-to-use264M-97
7.0 mL predilute ready-to-use264M-98

For in vitro diagnostic (IVD) use in Europe

25.0 mL predilute ready-to-use264M-90
0.1 mL concentrate264M-94
0.5 mL concentrate264M-95
1.0 mL concentrate264M-96
1.0 mL predilute ready-to-use264M-97
7.0 mL predilute ready-to-use264M-98

For research use only (RUO) in Japan

25.0 mL predilute ready-to-use (RUO)264M-90-RUO
0.1 mL concentrate (RUO)264M-94-RUO
0.5 mL concentrate (RUO)264M-95-RUO
1.0 mL concentrate (RUO)264M-96-RUO
1.0 mL predilute ready-to-use (RUO)264M-97-RUO
7.0 mL predilute ready-to-use (RUO)264M-98-RUO

 

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