Lymphocyte/germinal center cells are labelled by vimentin antibody in the tonsil.
Vimentin (V9) Mouse Monoclonal Antibody
Specialties: Anatomic Pathology
Updated: 2017-05-24 08:46:09
Vimentin is a 57kD, class-III, intermediate filament found in a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin. The anti-vimentin immunohistochemical reagent is also useful as a tissue process control reagent.1-9
- Ishii Y, et al. Two distinct antigen systems in human B lymphocytes: identification of cell surface and intracellular antigens using monoclonal antibodies. Clin Exp Immunol. 1984; 58:183-92.
- Davey FR, et al. Immunophenotyping of non-Hodgkin's lymphomas using a panel of antibodies on paraffin-embedded tissues. Am J Pathol. 1987; 129:54-63.
- Lane EB, et al. Co-expression of vimentin and cytokeratins in parietal endoderm cells of early mouse embryo. Nature. 1983; 303:701-4.
- Leader M, et al. Vimentin: an evaluation of its role as a tumour marker. Histopathology. 1987; 11:63-72.
- Ben-Ze’ev A. Differential control of cytokeratins and vimentin synthesis by cell-cell contact and cell spreading in cultured epithelial cells. J Cell Biol. 1984; 99:1424-33.
- Battifora H. Assessment of antigen damage in immunohistochemistry. The vimentin internal control. Am J Clin Pathol. 1991; 96:669-71.
- Takeyoshi I, et al. Skin metastasis from the spindle cell component in rectal carcinosarcoma. Hepatogastroenterology. 2000; 47:1611-4.
- Yaziji H, et al. Immunohistochemical analysis of gynecologic tumors. Int J Gynecol Pathol. 2001; 20:64-78.
- McCluggage WG. Recent advances in immunohistochemistry in gynaecological pathology. Histopathology. 2002; 40:309-26
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: tonsil, lymph node
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC34721040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 25 mL predilute | 347M-10 |
| 0.1 mL concentrate | 347M-14 |
| 0.5 mL concentrate | 347M-15 |
| 1 mL concentrate | 347M-16 |
| 1 mL predilute | 347M-17 |
| 7 mL predilute | 347M-18 |
For in vitro diagnostic (IVD) use in Canada
| 25 mL predilute | 347M-10 |
| 0.1 mL concentrate | 347M-14 |
| 0.5 mL concentrate | 347M-15 |
| 1 mL concentrate | 347M-16 |
| 1 mL predilute | 347M-17 |
| 7 mL predilute | 347M-18 |
For in vitro diagnostic (IVD) use in Europe
| 25 mL predilute | 347M-10 |
| 0.1 mL concentrate | 347M-14 |
| 0.5 mL concentrate | 347M-15 |
| 1 mL concentrate | 347M-16 |
| 1 mL predilute | 347M-17 |
| 7 mL predilute | 347M-18 |
For research use only (RUO) in Japan
| 25 mL predilute | 347M-10-RUO |
| 0.1 mL concentrate | 347M-14-RUO |
| 0.5 mL concentrate | 347M-15-RUO |
| 1 mL concentrate | 347M-16-RUO |
| 1 mL predilute | 347M-17-RUO |
| 7 mL predilute | 347M-18-RUO |
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