Vimentin (V9) Mouse Monoclonal Antibody

Vimentin
Lymphocyte/germinal center cells are labelled by vimentin antibody in the tonsil.

Vimentin (V9) Mouse Monoclonal Antibody

Specialties: Anatomic Pathology

Updated: 2017-05-24 08:46:09

Vimentin is a 57kD, class-III, intermediate filament found in a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin. The anti-vimentin immunohistochemical reagent is also useful as a tissue process control reagent.1-9

  1. Ishii Y, et al. Two distinct antigen systems in human B lymphocytes: identification of cell surface and intracellular antigens using monoclonal antibodies. Clin Exp Immunol. 1984; 58:183-92.
  2. Davey FR, et al. Immunophenotyping of non-Hodgkin's lymphomas using a panel of antibodies on paraffin-embedded tissues. Am J Pathol. 1987; 129:54-63.
  3. Lane EB, et al. Co-expression of vimentin and cytokeratins in parietal endoderm cells of early mouse embryo. Nature. 1983; 303:701-4.
  4. Leader M, et al. Vimentin: an evaluation of its role as a tumour marker. Histopathology. 1987; 11:63-72.
  5. Ben-Ze’ev A. Differential control of cytokeratins and vimentin synthesis by cell-cell contact and cell spreading in cultured epithelial cells. J Cell Biol. 1984; 99:1424-33.
  6. Battifora H. Assessment of antigen damage in immunohistochemistry. The vimentin internal control. Am J Clin Pathol. 1991; 96:669-71.
  7. Takeyoshi I, et al. Skin metastasis from the spindle cell component in rectal carcinosarcoma. Hepatogastroenterology. 2000; 47:1611-4.
  8. Yaziji H, et al. Immunohistochemical analysis of gynecologic tumors. Int J Gynecol Pathol. 2001; 20:64-78.
  9. McCluggage WG. Recent advances in immunohistochemistry in gynaecological pathology. Histopathology. 2002; 40:309-26

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: tonsil, lymph node
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

25 mL predilute347M-10
0.1 mL concentrate347M-14
0.5 mL concentrate347M-15
1 mL concentrate347M-16
1 mL predilute347M-17
7 mL predilute347M-18

For in vitro diagnostic (IVD) use in Canada

25 mL predilute347M-10
0.1 mL concentrate347M-14
0.5 mL concentrate347M-15
1 mL concentrate347M-16
1 mL predilute347M-17
7 mL predilute347M-18

For in vitro diagnostic (IVD) use in Europe

25 mL predilute347M-10
0.1 mL concentrate347M-14
0.5 mL concentrate347M-15
1 mL concentrate347M-16
1 mL predilute347M-17
7 mL predilute347M-18

For research use only (RUO) in Japan

25 mL predilute347M-10-RUO
0.1 mL concentrate347M-14-RUO
0.5 mL concentrate347M-15-RUO
1 mL concentrate347M-16-RUO
1 mL predilute347M-17-RUO
7 mL predilute347M-18-RUO

 

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