Cell line A & B
ROS1 Analyte Control
ROS1 is a receptor tyrosine kinase (RTK) encoded by the ROS1 gene. Genetic rearrangements can occur with many different partner genes.
Typically, ROS1 translocations or fusions are assessed by FISH. Recently, monoclonal antibodies for IHC that are effective in formalin-fixed, paraffin-embedded specimens, have entered the market. The ROS1 control consists of two cell lines: one with a SLC34A2-ROS1 translocation and resulting fusion protein; the other has no translocation and therefore no ROS1 protein expressed.
Specifications
- Cells are fixed in 10% neutral buffered formalin and paraffin wax embedded.
- Pre-cut sections are cut at 4µm, mounted on positively charged slides and baked overnight at 37°C.
- Cell microarrays (CMA) contain cores that are 2mm in diameter and 3-3.5mm in length. It is possible to obtain over 300-400 sections depending on thickness.
Package Inserts
IFU
Ordering Information
For research use only (RUO) in USA
| 2 unstained slides | HCL022 |
| 5 unstained slides | HCL023 |
| 1 cell microarray block | HCL024 |
For research use only (RUO) in Europe
| 2 unstained slides | HCL022 |
| 5 unstained slides | HCL023 |
| 1 cell microarray block | HCL024 |
For research use only (RUO) in Japan
| 2 unstained slides | HCL022 |
| 5 unstained slides | HCL023 |
| 1 cell microarray block | HCL024 |
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