PAX2 (EP235) Rabbit Monoclonal Antibody

Renal clear cell carcinoma stained with anti-PAX2.

PAX2 (EP235) Rabbit Monoclonal Antibody

Updated: 2017-05-24 08:46:09

PAX2 is a member of the paired box family of transcription factors, which is required for development and proliferation of the kidney, brain, and mllerian organs. PAX2 genes contain a highly conserved DNA sequence within the paired box region, which encodes a DNA-binding domain, enabling PAX proteins to bind the promoters of specific genes to transcriptionally regulate their expression. PAX2 is specifically expressed in the developing central nervous system, eye, ear, and urogenital tract, and is essential for the development of these organs. In normal adult tissues PAX2 was mainly detected in the urogenital system, including kidney, ureteric epithelium, fallopian tube epithelium, ovary and uterus. In tumors, PAX2 has been detected in renal cell carcinomas, Wilms' tumors, nephrogenic adenomas and papillary serous carcinoma of the ovary. PAX2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: fetal kidney, renal clear cell carcinoma
  • Dilution Range: 1:20*

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Ordering Information

For in vitro diagnostic (IVD) use in USA

1 mL concentrateAC-0236
0.1 mL concentrateAC-0236A

This product is not available in Canada

For in vitro diagnostic (IVD) use in Europe

1 mL concentrateAC-0236
0.1 mL concentrateAC-0236A

For research use only (RUO) in Japan

1 mL concentrateAC-0236
0.1 mL concentrateAC-0236A


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