p21 (EP147) Rabbit Monoclonal Antibody
p21WAF1, also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a protein that in humans is encoded by the CDKN1A gene located on chromosome 6 (6p21.2). The p21 protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. p21 is expressed in all adult human tissues. In tumors, the expression of p21 has been studied by immunohistochemical methods in a wide range of human tumors, such as gastric carcinoma, non-small cell lung carcinoma, and thyroid carcinoma. The expression of p21 is associated with favorable prognosis in various tumors.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic, nuclear
- Control: colon, colon carcinoma
- Dilution Range: 1:20*
Package Inserts
IFU:
IFU included with product
SDS:
Download your SDS
Ordering Information
For in vitro diagnostic (IVD) use in USA
| 1 mL concentrate | AC-0156 |
| 0.1 mL concentrate | AC-0156A |
This product is not available in Canada
For in vitro diagnostic (IVD) use in Europe
| 1 mL concentrate | AC-0156 |
| 0.1 mL concentrate | AC-0156A |
For research use only (RUO) in Japan
| 1 mL concentrate | AC-0156 |
| 0.1 mL concentrate | AC-0156A |
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