CD30 (EP154) Rabbit Monoclonal Antibody
CD30, TNF-receptor superfamily member, is a receptor for TNFSF8/CD30L. TRAF2 and TRAF5 can interact with this receptor and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and it also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. The CD30 antibody labels activated B and T cells. It has been useful in identifying Hodgkin's lymphoma, anaplastic large cell lymphomas (ALCL) and primary cutaneous CD30+ T-cell lymphoproliferative disorders. In non-lymphoid malignancies, CD30 reactivity has been reported in embryonal carcinomas (ECs), seminomas, and hepatocellular carcinomas.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic, membranous
- Control: tonsil, Hodgkin's lymphoma
- Dilution Range: 1:100 - 1:200 *
Package Inserts
IFU:
IFU included with product
SDS:
Download your SDS
Ordering Information
For in vitro diagnostic (IVD) use in USA
1 mL concentrate | AC-0141 |
0.1 mL concentrate | AC-0141A |
For in vitro diagnostic (IVD) use in Canada
1 mL concentrate | AC-0141 |
0.1 mL concentrate | AC-0141A |
For in vitro diagnostic (IVD) use in Europe
1 mL concentrate | AC-0141 |
0.1 mL concentrate | AC-0141A |
For research use only (RUO) in Japan
1 mL concentrate | AC-0141 |
0.1 mL concentrate | AC-0141A |
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