CD14 (EP128) Rabbit Monoclonal Antibody
CD14 is a 55-kDa protein found as a glycosylphosphatidylinositol (GPI)- anchored protein on the surface of monocytes, macrophages, and polymorphonuclear leukocytes, and as a soluble protein in the blood. Its main function is to serve as a receptor for lipopolysaccharide (LPS). Besides its role in endotoxin signaling, it has been proposed that CD14 is involved in the transportation of other lipids, cell-cell interactions during different immune responses, and recognition of apoptotic cells. CD14 is highly expressed on the surface of monocytes/macrophages and strongly up-regulated during the differentiation of monocytic precursor cells into mature monocytes. Therefore, CD14 has been commonly used as a differentiation marker for monocytes/macrophages. An antibody to CD14 also labels Langerhans' cells and dendritic cells.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic, membranous
- Control: tonsil, histiocytic sarcoma
- Dilution Range: 1:100 - 1:200*
Package Inserts
IFU:
IFU included with product
SDS:
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Ordering Information
For in vitro diagnostic (IVD) use in USA
1 mL concentrate | AC-0123 |
0.1 mL concentrate | AC-0123A |
This product is not available in Canada
For in vitro diagnostic (IVD) use in Europe
1 mL concentrate | AC-0123 |
0.1 mL concentrate | AC-0123A |
For research use only (RUO) in Japan
1 mL concentrate | AC-0123 |
0.1 mL concentrate | AC-0123A |
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