CD14 (EP128) Rabbit Monoclonal Antibody

Tonsil stained with anti-CD14

CD14 (EP128) Rabbit Monoclonal Antibody

Updated: 2017-05-24 08:46:09

CD14 is a 55-kDa protein found as a glycosylphosphatidylinositol (GPI)- anchored protein on the surface of monocytes, macrophages, and polymorphonuclear leukocytes, and as a soluble protein in the blood. Its main function is to serve as a receptor for lipopolysaccharide (LPS). Besides its role in endotoxin signaling, it has been proposed that CD14 is involved in the transportation of other lipids, cell-cell interactions during different immune responses, and recognition of apoptotic cells. CD14 is highly expressed on the surface of monocytes/macrophages and strongly up-regulated during the differentiation of monocytic precursor cells into mature monocytes. Therefore, CD14 has been commonly used as a differentiation marker for monocytes/macrophages. An antibody to CD14 also labels Langerhans' cells and dendritic cells.


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: tonsil, histiocytic sarcoma
  • Dilution Range: 1:100 - 1:200*

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For in vitro diagnostic (IVD) use in USA

1 mL concentrateAC-0123
0.1 mL concentrateAC-0123A

This product is not available in Canada

For in vitro diagnostic (IVD) use in Europe

1 mL concentrateAC-0123
0.1 mL concentrateAC-0123A

For research use only (RUO) in Japan

1 mL concentrateAC-0123
0.1 mL concentrateAC-0123A


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