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BCL6 (GI191E/A8)

Mouse Monoclonal


BCL6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein. Antibodies to this protein stain the germinal center cells (benign and malignant) in lymphoid follicles, and interfollicular malignant cells in follicular lymphoma, diffuse large B-cell lymphomas, and Burkitt lymphoma, as well as the majority of tumor cells in nodular lymphocyte predominant Hodgkin lymphoma. 1-3 Anti-BCL6 rarely stains mantle cell lymphoma and mucosa associated lymphoid tissue (MALT) lymphoma.2 BCL6 expression is seen in approximately 68% of ALK+ anaplastic large cell lymphomas (ALCL) and 28% of ALK- ALCL, NK/T-cell lymphoma (27%), peripheral T-cell lymphoma, NOS (8.6%), and T-lymphoblastic lymphoma (9.1%).4 BCL6 expression can also be observed in angioimmunoblastic T-cell lymphoma (66%-96%).5

BCL6 is protected by U.S. patents 6,174,997 and 6,783,94 (Cancer Genetics, Inc.)

Specialties: Hematopathology

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: tonsil
  • Isotype: IgG1
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

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Last updated: 2016-09-29 13:18:40

BCL6
BCL6 (GI19E/A8) on tonsil, germinal centers.

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Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: tonsil
  • Isotype: IgG1
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 227M-94
0.5 ml, concentrate 227M-95
1 ml, concentrate 227M-96
1 ml, predilute 227M-97
7 ml, predilute 227M-98
25 ml, predilute 227M-90

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 227M-94
0.5 ml, concentrate 227M-95
1 ml, concentrate 227M-96
1 ml, predilute 227M-97
7 ml, predilute 227M-98
25 ml, predilute 227M-90

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 227M-94
0.5 ml, concentrate 227M-95
1 ml, concentrate 227M-96
1 ml, predilute 227M-97
7 ml, predilute 227M-98
25 ml, predilute 227M-90

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 227M-94 (RUO)
0.5 ml, concentrate 227M-95 (RUO)
1 ml, concentrate 227M-96 (RUO)
1 ml, predilute 227M-97 (RUO)
7 ml, predilute 227M-98 (RUO)
25 ml, predilute 227M-90 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: tonsil
  • Isotype: IgG1
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

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