CD11c (5D11) Mouse Monoclonal Antibody

CD11c
Hairy cell leukemia cells show a moderate membranous staining reaction by CD11c antibody.

CD11c (5D11) Mouse Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

CD11c is an adhesion receptor of the leukocyte function-associated family of molecules. Reportedly CD11c is expressed in hairy cell leukemia whereas the majority of other small B-cell lymphomas do not express CD11c antigen. This indicates that immunohistochemical staining of formalin-fixed biopsies with anti-CD11c can be useful for identification of hairy cell leukemia.1-4

  1. Korinna J, et al. A novel CD I monoclonal antibody effective in formalin-fixed tissue for the diagnosis of hairy cell leukemia. Pathobiology. 2008; 75:252-6.
  2. Went PT, et al. High specificity of combined TRAP and DBA.44 expression for hairy cell leukaemia. Am J Surg Pathol. 2005; 29:474-8.
  3. Miranda RN, et al. Immunohistochemical detection of cyclin Dl using optimized conditions is highly specific for mantle cell lymphoma and hairy cell leukaemia. Modem Pathology. 2000; 13:1308-14.
  4. Marotta G, et al. Expression of the CD11c antigen in B-cell chronic lymphoproliferative disorders. Leuk Lymphoma. 2000; 37:145-9.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: hairy cell leukemia, granulocytes, monocytes, bone marrow
  • Dilution Range: 1:20-1:80*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate111M-14
0.5 mL concentrate111M-15
1 mL concentrate111M-16
1 mL predilute111M-17
7 mL predilute111M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate111M-14
0.5 mL concentrate111M-15
1 mL concentrate111M-16
1 mL predilute111M-17
7 mL predilute111M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate111M-14
0.5 mL concentrate111M-15
1 mL concentrate111M-16
1 mL predilute111M-17
7 mL predilute111M-18

For research use only (RUO) in Japan

0.1 mL concentrate111M-14-RUO
0.5 mL concentrate111M-15-RUO
1 mL concentrate111M-16-RUO
1 mL predilute111M-17-RUO
7 mL predilute111M-18-RUO

 

To request information on this product in additional countries, please click the button below.

Request More Information