CD25 antibody stains neoplastic cells of adult T-cell leukemia/lymphoma in a cytoplasmic and Golgi zone pattern.
CD25 (4C9) Mouse Monoclonal Antibody
Specialties: Hematopathology
Updated: 2017-05-24 08:46:09
CD25, Interleukin-2 receptor alpha chain, is the alpha subunit of the cell surface receptor which regulates regulatory T-cells.1 CD25 has been detected in various hematological malignancies including adult T-cell leukemia/lymphoma, and hairy cell leukemia.2-3
- Létourneau S, et al. IL-2- and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets. Clin Immunol. 2009; 123:758-62.
- De Totero D, et al. Expression of the IL2 receptor alpha, beta and gamma chains in hairy cell leukemia. Leuk Lymphoma. 1994; 104:412-9.
- Qayyum S, et al. Adult T-Cell Leukemia/Lymphoma. Archives of Pathology & Lab Med. 2014; 138:282-6.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic, membranous
- Control: lesions of mastocytosis
- Dilution Range: 1:10-1:50*
Package Inserts
IFU
- IVD Rev. 5.0 (CMC12521050)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 125M-14 |
| 0.5 mL concentrate | 125M-15 |
| 1 mL concentrate | 125M-16 |
| 1 mL predilute | 125M-17 |
| 7 mL predilute | 125M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 125M-14 |
| 0.5 mL concentrate | 125M-15 |
| 1 mL concentrate | 125M-16 |
| 1 mL predilute | 125M-17 |
| 7 mL predilute | 125M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 125M-14 |
| 0.5 mL concentrate | 125M-15 |
| 1 mL concentrate | 125M-16 |
| 1 mL predilute | 125M-17 |
| 7 mL predilute | 125M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 125M-14-RUO |
| 0.5 mL concentrate | 125M-15-RUO |
| 1 mL concentrate | 125M-16-RUO |
| 1 mL predilute | 125M-17-RUO |
| 7 mL predilute | 125M-18-RUO |
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