CD25 (4C9) Mouse Monoclonal Antibody

CD25
CD25 antibody stains neoplastic cells of adult T-cell leukemia/lymphoma in a cytoplasmic and Golgi zone pattern.

CD25 (4C9) Mouse Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

CD25, Interleukin-2 receptor alpha chain, is the alpha subunit of the cell surface receptor which regulates regulatory T-cells.1 CD25 has been detected in various hematological malignancies including adult T-cell leukemia/lymphoma, and hairy cell leukemia.2-3

  1. Létourneau S, et al. IL-2- and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets. Clin Immunol. 2009; 123:758-62.
  2. De Totero D, et al. Expression of the IL2 receptor alpha, beta and gamma chains in hairy cell leukemia. Leuk Lymphoma. 1994; 104:412-9.
  3. Qayyum S, et al. Adult T-Cell Leukemia/Lymphoma. Archives of Pathology & Lab Med. 2014; 138:282-6.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: lesions of mastocytosis
  • Dilution Range: 1:10-1:50*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate125M-14
0.5 mL concentrate125M-15
1 mL concentrate125M-16
1 mL predilute125M-17
7 mL predilute125M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate125M-14
0.5 mL concentrate125M-15
1 mL concentrate125M-16
1 mL predilute125M-17
7 mL predilute125M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate125M-14
0.5 mL concentrate125M-15
1 mL concentrate125M-16
1 mL predilute125M-17
7 mL predilute125M-18

For research use only (RUO) in Japan

0.1 mL concentrate125M-14-RUO
0.5 mL concentrate125M-15-RUO
1 mL concentrate125M-16-RUO
1 mL predilute125M-17-RUO
7 mL predilute125M-18-RUO

 

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