HBME-1 (HBME-1) Mouse Monoclonal Antibody

HBME-1
HBME-1 on pleura.

HBME-1 (HBME-1) Mouse Monoclonal Antibody

Specialties: Cytopathology Head/Neck Pathology

Updated: 2017-05-24 08:46:09

Hector Battifora mesothelial-1 (HBME-1) is a membrane antigen that exists in the microvilli of mesothelial cells and other epithelial cells.1 Anti-HBME-1 labels thyroid papillary carcinoma and follicular carcinoma but not normal thyroid making it a valuable marker for distinguishing thyroid malignacies from benign thyroid lesions.2 It has also been demonstrated to label mesothelial cells, both benign and malignant (malignant mesothelioma) and thus can aid in the identification of mesothelioma.2

  1. Cheung CC, et al. Immunohistochemical diagnosis of papillary thyroid carcinoma. Mod Pathol. 2001; 14:338–42
  2. Bateman AC, et al. Immunohistochemical phenotype of malignant mesothelioma: predictive value of CA125 and HBME-1 expression. Histopathology. 1997; 30:49-56.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: mesothelioma
  • Dilution Range: 1:25-1:100*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate283M-14
0.5 mL concentrate283M-15
1 mL concentrate283M-16
1 mL predilute283M-17
7 mL predilute283M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate283M-14
0.5 mL concentrate283M-15
1 mL concentrate283M-16
1 mL predilute283M-17
7 mL predilute283M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate283M-14
0.5 mL concentrate283M-15
1 mL concentrate283M-16
1 mL predilute283M-17
7 mL predilute283M-18

For research use only (RUO) in Japan

0.1 mL concentrate283M-14-RUO
0.5 mL concentrate283M-15-RUO
1 mL concentrate283M-16-RUO
1 mL predilute283M-17-RUO
7 mL predilute283M-18-RUO

 

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