PNL2 (PNL2) Mouse Monoclonal Antibody

PNL2
Melanoma tumor cells are stained by the PNL2 antibody in a cytoplasmic pattern.

PNL2 (PNL2) Mouse Monoclonal Antibody

Specialties: Dermatopathology

Updated: 2017-05-24 08:46:09

Anti-PNL2 is useful as an immunohistochemical reagent to stain melanocytes and tumors derived therefrom. Anti-PNL2 reactivity is identified in the cytoplasm of cutaneous and oral mucosal melanocytes. Anti-PNL2 labels intraepidermal nevi, while the dermal components of compound nevi are largely non-reactive.1-4

  1. Rochaix P, et al. PNL2, a new monoclonal antibody directed against a fixative-resistant melanocyte antigen. Mod Pathol. 2003; 16:481-90.
  2. Klaus J, et al. Immunohistochemical analysis of novel monoclonal antibody PNL2 and comparison with other melanocyte differentiation markers. Am J Surg Pathol. 2005; 29:400-6.
  3. Morris LG, et al. PNL2 melanocytic marker in immunohistochemical evaluation of primary mucosal melanoma of the head and neck. Head Neck. 2008; 30:771-5.
  4. Zhe X, et al. Combined smooth muscle and melanocytic differentiation in lymphangioleiomyomatosis. J Histo and Cyto. 2004; 52:1537-42.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: melanoma
  • Dilution Range: 1:25-1:100*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate365M-94
0.5 mL concentrate365M-95
1 mL concentrate365M-96
1 mL predilute365M-97
7 mL predilute365M-98

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate365M-94
0.5 mL concentrate365M-95
1 mL concentrate365M-96
1 mL predilute365M-97
7 mL predilute365M-98

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate365M-94
0.5 mL concentrate365M-95
1 mL concentrate365M-96
1 mL predilute365M-97
7 mL predilute365M-98

For research use only (RUO) in Japan

0.1 mL concentrate365M-94-RUO
0.5 mL concentrate365M-95-RUO
1 mL concentrate365M-96-RUO
1 mL predilute365M-97-RUO
7 mL predilute365M-98-RUO

 

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