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Microphthalmia Transcription Factor (MiTF) (C5/D5)

Mouse Monoclonal


Microphthalmia (MiTF) is a transcription factor implicated in pigmentation, bone development and in mast cells. Various forms of MiTF exist ranging from 50-70 kD in size. This antibody targets the 52-56 kD range. This antibody has been useful in identifying malignant melanoma, and distinguishing mast cell lesions from lesions of myeloid derivation. A relatively rare class of tumors known as PEComas (tumors showing perivascular epithelioid cell differentiation) express MiTF in a high percentage of cases (~90%).

Specialties: Dermatopathology

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: melanoma
  • Isotype: IgG1 & IgG1
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Leica Bond
    Protocol J: ER2/20
  • Leica Bond
    Protocol F: ER2/20
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

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*Note: IFUs with the prefix RUO or ASR are only available for download in English.


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Last updated: 2016-09-29 13:18:40

Microphthalmia Transcription Factor (MiTF)
Anti-MiTF labels the nucleus and cytoplasm of tumor cells in melanoma.

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Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: melanoma
  • Isotype: IgG1 & IgG1
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Leica Bond
    Protocol J: ER2/20
  • Leica Bond
    Protocol F: ER2/20
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 284M-94
0.5 ml, concentrate 284M-95
1 ml, concentrate 284M-96
1 ml, predilute 284M-97
7 ml, predilute 284M-98
25 ml, predilute 284M-90

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 284M-94
0.5 ml, concentrate 284M-95
1 ml, concentrate 284M-96
1 ml, predilute 284M-97
7 ml, predilute 284M-98
25 ml, predilute 284M-90

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 284M-94
0.5 ml, concentrate 284M-95
1 ml, concentrate 284M-96
1 ml, predilute 284M-97
7 ml, predilute 284M-98
25 ml, predilute 284M-90

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 284M-94 (RUO)
0.5 ml, concentrate 284M-95 (RUO)
1 ml, concentrate 284M-96 (RUO)
1 ml, predilute 284M-97 (RUO)
7 ml, predilute 284M-98 (RUO)
25 ml, predilute 284M-90 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: melanoma
  • Isotype: IgG1 & IgG1
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Leica Bond
    Protocol J: ER2/20
  • Leica Bond
    Protocol F: ER2/20
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

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