Microphthalmia Transcription Factor (MiTF) (C5/D5) Mouse Monoclonal Antibody

Microphthalmia Transcription Factor (MiTF)
Anti-MiTF labels the nucleus and cytoplasm of tumor cells in melanoma.

Microphthalmia Transcription Factor (MiTF) (C5/D5) Mouse Monoclonal Antibody

Specialties: Dermatopathology

Updated: 2018-01-11 11:23:39

Mi is a transcription factor implicated in pigmentation, bone development and in mast cells. Various forms of Mi exist ranging from 50-70 kD in size. This antibody targets the 52-56 kD range. This antibody has been useful in identifying malignant melanoma.1-5

  1. Liegl B, et al. Primary cutaneous PEComa: distinctive clear cell lesions of skin. Am J Surg Pathol. 2008; 32:608-14.
  2. Righi A, et al. PEComa: another member of the MiT tumor family? Int J Surg Pathol. 2008; 16:16-20.
  3. Weinreb I, et al. Perivascular epithelioid cell neoplasms (PEComas): four malignant cases expanding the histopathological spectrum and a description of a unique finding. Virchows Arch. 2007; 450:463-70. 
  4. Ohsie SJ, et al. Immunohistochemical characteristics of melanoma. J Cutan Pathol. 2008; 35:433-44.
  5. Hornick JL, et al. Sclerosing PEComa: clinicopathologic analysis of a distinctive variant with a predilection for the retroperitoneum. Am J Surg Pathol. 2008; 32:493-501.

Specifications


  • Reactivity: paraffin
  • Control: Melanoma (Nuclear)
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

25.0 mL predilute ready-to-use284M-90
0.1 mL concentrate284M-94
0.5 mL concentrate284M-95
1.0 mL concentrate284M-96
1.0 mL predilute ready-to-use284M-97
7.0 mL predilute ready-to-use284M-98

For in vitro diagnostic (IVD) use in Canada

25.0 mL predilute ready-to-use284M-90
0.1 mL concentrate284M-94
0.5 mL concentrate284M-95
1.0 mL concentrate284M-96
1.0 mL predilute ready-to-use284M-97
7.0 mL predilute ready-to-use284M-98

For in vitro diagnostic (IVD) use in Europe

25.0 mL predilute ready-to-use284M-90
0.1 mL concentrate284M-94
0.5 mL concentrate284M-95
1.0 mL concentrate284M-96
1.0 mL predilute ready-to-use284M-97
7.0 mL predilute ready-to-use284M-98

For research use only (RUO) in Japan

25.0 mL predilute ready-to-use (RUO)284M-90-RUO
0.1 mL concentrate (RUO)284M-94-RUO
0.5 mL concentrate (RUO)284M-95-RUO
1.0 mL concentrate (RUO)284M-96-RUO
1.0 mL predilute ready-to-use (RUO)284M-97-RUO
7.0 mL predilute ready-to-use (RUO)284M-98-RUO

 

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