CD163 (MRQ-26) Mouse Monoclonal Antibody

CD163
CD163 (MRQ-26) on placenta.

CD163 (MRQ-26) Mouse Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

CD163, also known as scavenger receptor cysteine-rich type 1 protein M130,1 is an acute phase-regulated and signal-inducing transmembrane protein,2 found exclusively on cells of monocytic origin.1 CD163 plays a critical role in macrophage clearance and endocytosis of hemoglobin/haptoglobin complexes.2 Therefore, CD163 contributes to the anti-inflammatory response and protects tissues from oxidative and inflammatory hemoglobin.3 Anti-CD163 labels cells of monocytic-macrophage lineage, with expression in bone marrow3 and histiocytic neoplasms.4

  1. Buechler C, et al. J Leukoc Biol. 2000; 67:97-103.
  2. Kristiansen M, et al. Nature. 2001; 409:198-201.
  3. Etzerodt A. et al. Antioxid Redox Signal. 2013; 18: 2352-63.
  4. Backe E, et al. J Clin Pathol. 1991; 44:936-45.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: inflamed tissue
  • Dilution Range: 1:10-1:50*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate163M-14
0.5 mL concentrate163M-15
1 mL concentrate163M-16
1 mL predilute163M-17
7 mL predilute163M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate163M-14
0.5 mL concentrate163M-15
1 mL concentrate163M-16
1 mL predilute163M-17
7 mL predilute163M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate163M-14
0.5 mL concentrate163M-15
1 mL concentrate163M-16
1 mL predilute163M-17
7 mL predilute163M-18

For research use only (RUO) in Japan

0.1 mL concentrate163M-14-RUO
0.5 mL concentrate163M-15-RUO
1 mL concentrate163M-16-RUO
1 mL predilute163M-17-RUO
7 mL predilute163M-18-RUO

 

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