Cell Marque Portfolio

PAX-5 (EP156)

Rabbit Monoclonal


PAX-5 encodes for B-cell-specific activator protein (BSAP), a marker for B-cells, including B-lymphoblastic neoplasms and maturation stage. It is found in most cases of mature and precursor B-cell non-Hodgkin lymphomas/leukemias. In approximately 97% of cases of classic Hodgkin lymphoma, Reed-Sternberg cells express PAX-5.4 PAX-5 is not detected in multiple myeloma and solitary plasmacytoma, making it useful for such differentiation.1,3 Diffuse large B-cell lymphomas do express PAX-5, save for those with terminal B-cell differentiation. T-cell neoplasms do not stain with anti-PAX-5. There is a strong association with CD20 expression.1-4

Specialties: Hematopathology

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: tonsil
  • Isotype: IgG
  • Dilution Range: 1:50-1:200*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?



*Note: IFUs with the prefix RUO or ASR are only available for download in English.


Click here to learn about keycodes

References


  1. Torlakovic E, et al. Am J Surg Pathol. 2002; 26:1343-50.
  2. Willenbrock K, et al. Lab Invest. 2002; 82:1103-9.
  3. Falini B, et al. Blood. 2002; 99:409-26.
  4. Schwering I, et al. Blood. 2003; 101:1505-12.

Literature

Last updated: 2016-09-29 13:18:40

PAX-5
Nuclear labelling of germinal center and mantle zone cells by PAX-5 antibody on hyperplastic lymph node.

Mouse over to zoom, use scroll wheel to zoom in/out

Tap image once to activate zoom lens


Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: tonsil
  • Isotype: IgG
  • Dilution Range: 1:50-1:200*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

References


  1. Torlakovic E, et al. Am J Surg Pathol. 2002; 26:1343-50.
  2. Willenbrock K, et al. Lab Invest. 2002; 82:1103-9.
  3. Falini B, et al. Blood. 2002; 99:409-26.
  4. Schwering I, et al. Blood. 2003; 101:1505-12.

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 312R-24
0.5 ml, concentrate 312R-25
1 ml, concentrate 312R-26
1 ml, predilute 312R-27
7 ml, predilute 312R-28
25 ml, predilute 312R-20

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 312R-24
0.5 ml, concentrate 312R-25
1 ml, concentrate 312R-26
1 ml, predilute 312R-27
7 ml, predilute 312R-28
25 ml, predilute 312R-20

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 312R-24
0.5 ml, concentrate 312R-25
1 ml, concentrate 312R-26
1 ml, predilute 312R-27
7 ml, predilute 312R-28
25 ml, predilute 312R-20

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 312R-24 (RUO)
0.5 ml, concentrate 312R-25 (RUO)
1 ml, concentrate 312R-26 (RUO)
1 ml, predilute 312R-27 (RUO)
7 ml, predilute 312R-28 (RUO)
25 ml, predilute 312R-20 (RUO)

Literature

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: tonsil
  • Isotype: IgG
  • Dilution Range: 1:50-1:200*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

References


  1. Torlakovic E, et al. Am J Surg Pathol. 2002; 26:1343-50.
  2. Willenbrock K, et al. Lab Invest. 2002; 82:1103-9.
  3. Falini B, et al. Blood. 2002; 99:409-26.
  4. Schwering I, et al. Blood. 2003; 101:1505-12.
Request More Information