CD4 (EP204) Rabbit Monoclonal Antibody

CD4
Interfollicular T-lymphocytes express CD4 antigen in the cytoplasm of the lymphocytes.

CD4 (EP204) Rabbit Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

CD4 is a 55 kD glycoprotein expressed on the surface of T-helper/regulatory T-cells, monocytes, macrophages, and dendritic cells. Anti-CD4 is used in the immunophenotyping of lymphoproliferative disorders.1 The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4+ CD8-.2 As with other T-cell antigens, CD4 may be aberrantly expressed in neoplastic T-cells so that the evaluation of such tumors requires the application of a panel of markers in order to identify tumors with CD4 aberrant expression.1-3

  1. Leong AS-Y, et al. Greenwich Medical Media Ltd. 2003.
  2. Akiyama T, et al. Pathol Int. 2008; 58:626-34.
  3. Garcia-Herrera A, et al. J Clin Oncol. 2008; 26:3364-71.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: tonsil, lymph node
  • Dilution Range: 1:25-1:100*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate104R-24
0.5 mL concentrate104R-25
1 mL concentrate104R-26
1 mL predilute104R-27
7 mL predilute104R-28

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate104R-24
0.5 mL concentrate104R-25
1 mL concentrate104R-26
1 mL predilute104R-27
7 mL predilute104R-28

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate104R-24
0.5 mL concentrate104R-25
1 mL concentrate104R-26
1 mL predilute104R-27
7 mL predilute104R-28

For research use only (RUO) in Japan

0.1 mL concentrate104R-24-RUO
0.5 mL concentrate104R-25-RUO
1 mL concentrate104R-26-RUO
1 mL predilute104R-27-RUO
7 mL predilute104R-28-RUO

 

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