Cell Marque Portfolio

FOXA1 (2F83)

Mouse Monoclonal


Forkhead box A1 (FOXA1), also known as hepatocyte nuclear factor 3 alpha (HNF3a), is a transcription factor expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. It has been reported to co-express with ER in breast carcinoma, predominantly in luminal subtype A.1-2 FOXA1 expression has been identified in 42% - 75% of invasive carcinoma of the breast.1-2 Of the FOXA1-positive breast invasive carcinomas, 83% were comprised of ER+/PR+/Her2+ luminal A subtype.1 The results indicate that anti-FOXA1 is useful in the sub-classification of breast carcinoma.

Specialties: Breast/Gynecological Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: breast carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/16min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

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Last updated: 2015-10-15 12:16:34

FOXA1
FOXA1 nuclear expression in invasive ductal carcinoma of the breast is detected by FOXA1 antibody.

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Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: breast carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/16min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 405M-14
0.5 ml, concentrate 405M-15
1 ml, concentrate 405M-16
1 ml, predilute 405M-17
7 ml, predilute 405M-18

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 405M-14
0.5 ml, concentrate 405M-15
1 ml, concentrate 405M-16
1 ml, predilute 405M-17
7 ml, predilute 405M-18

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 405M-14
0.5 ml, concentrate 405M-15
1 ml, concentrate 405M-16
1 ml, predilute 405M-17
7 ml, predilute 405M-18

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 405M-14 (RUO)
0.5 ml, concentrate 405M-15 (RUO)
1 ml, concentrate 405M-16 (RUO)
1 ml, predilute 405M-17 (RUO)
7 ml, predilute 405M-18 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: breast carcinoma
  • Isotype: IgG1/k
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/16min @ 37°C
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

Request More Information