PGP 9.5 Rabbit Polyclonal Antibody

PGP 9.5
Auerbach plexus of nerve tissue is labelled by PGP 9.5 antibody on small bowel tissue.

PGP 9.5 Rabbit Polyclonal Antibody

Specialties: Anatomic Pathology

Updated: 2018-01-11 13:22:49

Protein gene product 9.5 (PGP 9.5), also known as ubiquitin carboxyl-terminal hydrolase-1 (UCHL-1), is a 27 kDa protein originally isolated from whole brain extracts.1 Although PGP 9.5 expression in normal tissues was originally felt to be strictly confined to neurons and neuroendocrine cells,2 it has been subsequently documented in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts.1 A plethora of mesenchymal neoplasms have demonstrated PGP 9.5 expression.1,3,4

  1. Campbell LK, et al. Protein gene product 9.5 (PGP 9.5) is not a specific marker of neural and nerve sheath tumors: an immunohistochemical study of 95 mesenchymal neoplasms. Mod Pathol. 2003; 16:963-9.
  2. Bassotti G, et al. Interstitial cells of Cajal, enteric nerves, and glial cells in colonic diverticular disease. J Clin Pathol. 2005; 58:973-7.
  3. Mahalingam M, et al. Expression of PGP 9.5 in granular cell nerve sheath tumors: and immunohistochemical study of six cases. J Cutan Pathol. 2001; 28:282-6.
  4. Mahalingam M, et al. Multiple cellular neurothekeomas—a case report and review on the role of immunohistochemistry as a histo-logic adjunct. J Cutan Pathol. 2006; 33:51-6.

Specifications


  • Reactivity: paraffin
  • Control: Nerve Tissue (Cytoplasmic)
  • Dilution Range: 1:100-1:500 *

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate318A-14
0.5 mL concentrate318A-15
1.0 mL concentrate318A-16
1.0 mL predilute ready-to-use318A-17
7.0 mL predilute ready-to-use318A-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate318A-14
0.5 mL concentrate318A-15
1.0 mL concentrate318A-16
1.0 mL predilute ready-to-use318A-17
7.0 mL predilute ready-to-use318A-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate318A-14
0.5 mL concentrate318A-15
1.0 mL concentrate318A-16
1.0 mL predilute ready-to-use318A-17
7.0 mL predilute ready-to-use318A-18

For research use only (RUO) in Japan

0.1 mL concentrate (RUO)318A-14-RUO
0.5 mL concentrate (RUO)318A-15-RUO
1.0 mL concentrate (RUO)318A-16-RUO
1.0 mL predilute ready-to-use (RUO)318A-17-RUO
7.0 mL predilute ready-to-use (RUO)318A-18-RUO

 

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