eIF-4E (EP280) Rabbit Monoclonal Antibody

eIF-4E
Breast carcinoma stained with anti-eIF-4E

eIF-4E (EP280) Rabbit Monoclonal Antibody

Updated: 2017-05-24 08:46:09

Eukaryotic initiation factor 4E (eIF-4E), a 25-kDa cap binding protein, delivers cellular mRNAs to the eIF4F translation initiation complex by binding the 5'-cap structure of these mRNAs. Studies suggested that increased expression and activity of eIF-4E might be one of the key effects on oncogene expression, resulting in neoplastic transformation. eIF-4E is overexpressed in many types of cancers, including carcinoma of the breast, colon, bladder, cervix, lung, and squamous cell carcinoma of the head and neck. Increased expression of eIF-4E has been associated with tumor progression in breast cancer, prostate cancer, and acute myeloid leukemia (AML).

Specifications


  • Dilution Range: 1:100-1:200*

Package Inserts


IFU:
IFU included with product

SDS:
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Ordering Information

For research use only (RUO) in USA

0.1 mL concentrateAC-0262RUO
1 mL concentrateAC-0262RUOC

This product is not available in Canada

For research use only (RUO) in the EU

0.1 mL concentrateAC-0262RUO
1 mL concentrateAC-0262RUOC

For research use only (RUO) in Japan

0.1 mL concentrateAC-0262RUO
1 mL concentrateAC-0262RUOC

 

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