Cathepsin D (EP81) Rabbit Monoclonal Antibody

Cathepsin D
Breast cancer stained with anti-Cathepsin D

Cathepsin D (EP81) Rabbit Monoclonal Antibody

Updated: 2017-05-24 08:46:09

Cathepsin D is a ubiquitously expressed lysosomal protease that is involved in proteolytic degradation, cell invasion, and apoptosis. It is suspected to play important roles in protein catabolism, antigen processing, degenerative diseases, and cancer progression. Cathepsin D is present in many types of cancer cells. In breast cancer, it is induced by estrogens and its expression is correlated with a higher risk of metastasis and poor disease-free survival. Extensive studies have been also performed to evaluate the clinical and therapeutic implication of Cathepsin D expression in nongynecological solid tumors. Although conflicting results have been observed in some reports, evidence emerging from these studies indicated that Cathepsin D seems to facilitate early stages of tumor progression such as cell proliferation and local dissemination.

Specifications


  • Dilution Range: 1:100 - 1:200*

Package Inserts


IFU:
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Ordering Information

For research use only (RUO) in USA

0.1 mL concentrateAC-0090RUO
1 mL concentrateAC-0090RUOC

This product is not available in Canada

For research use only (RUO) in the EU

0.1 mL concentrateAC-0090RUO
1 mL concentrateAC-0090RUOC

For research use only (RUO) in Japan

0.1 mL concentrateAC-0090RUO
1 mL concentrateAC-0090RUOC

 

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