Cell Marque Portfolio

PMS2 (EPR3947)

Rabbit Monoclonal


PMS2 is a mismatch repair protein that is deficient in a high proportion of patients with microsatellite instability (MSI-H). It has been suggested that the deficiencies in DNA mismatch repair protein(s) can be seen in some malignancies such as hereditary nonpolyposis colorectal cancer (HNPCC) and endometrial cancer. Anti-PMS2 may be useful in identification of PMS2 protein in variety of normal and neoplastic tissues and identification of loss of MLH1 in tumors with MSI genotype.1-7 Anti-PMS2 is best utilized in an IHC panel that includes anti-MSH6, anti-MSH2, and anti-MLH1.

Specialties: Gastrointestinal (GI) Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: colon
  • Isotype: IgG
  • Dilution Range: N/A*

Protocols


  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

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Last updated: 2016-09-29 13:18:40

PMS2
Nuclear labelling of carcinoma cells by PMS2 antibody on colon adenocarcinoma.

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Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: colon
  • Isotype: IgG
  • Dilution Range: N/A*

Protocols


  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
1 ml, predilute 288R-17
7 ml, predilute 288R-18
25 ml, predilute 288R-10

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
1 ml, predilute 288R-17
7 ml, predilute 288R-18
25 ml, predilute 288R-10

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
1 ml, predilute 288R-17
7 ml, predilute 288R-18
25 ml, predilute 288R-10

For research use only (RUO) in Japan

DescriptionCat. No.
1 ml, predilute 288R-17 (RUO)
7 ml, predilute 288R-18 (RUO)
25 ml, predilute 288R-10 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: colon
  • Isotype: IgG
  • Dilution Range: N/A*

Protocols


  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/30-60minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

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