C3d Rabbit Polyclonal Antibody

C3d
C3d polyclonal antibody shows moderate cytoplasmic labelling of peritubular capillary endothelial cells on the acute rejection kidney.

C3d Rabbit Polyclonal Antibody

Specialties: Anatomic Pathology

Updated: 2017-05-24 08:46:09

Complement component C3 is an integral part of the classical, lectin, and alternative complement pathways, and its cleavage products are involved in immune responses such as opsonization and cell lysis. C3d is a fragment of C3 that normally binds to pathogen surfaces to promote B-cell activation. However, deposition of C3d has also been observed in peritubular capillaries of transplanted kidneys undergoing acute allograft rejection.1-3

  1. Bickerstaff A, et al. Am J Pathol. 2008; 173:347-57.
  2. Kuypers DR, et al. Transplantation. 2003; 76:102-8.
  3. Eggertsen G, et al. APMIS. 2001; 109:825-34.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: acute rejected kidney transplant
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate403A-74
0.5 mL concentrate403A-75
1 mL concentrate403A-76
1 mL predilute403A-77
7 mL predilute403A-78

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate403A-74
0.5 mL concentrate403A-75
1 mL concentrate403A-76
1 mL predilute403A-77
7 mL predilute403A-78

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate403A-74
0.5 mL concentrate403A-75
1 mL concentrate403A-76
1 mL predilute403A-77
7 mL predilute403A-78

For research use only (RUO) in Japan

0.1 mL concentrate403A-74-RUO
0.5 mL concentrate403A-75-RUO
1 mL concentrate403A-76-RUO
1 mL predilute403A-77-RUO
7 mL predilute403A-78-RUO

 

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