TSH Rabbit Polyclonal Antibody

TSH
Cells in adenohypophysis are labelled by anti-TSH.

TSH Rabbit Polyclonal Antibody

Specialties: Anatomic Pathology Neuropathology

Updated: 2017-05-24 08:46:09

Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a peptide hormone synthesized and secreted by thyrotrops in the anterior pituitary gland which regulate the endocrine function of the thyroid gland. TSH is a glycoprotein and consists of two subunits which are non-covalently bound to one another. Anti-TSH reacts with TSH-producing cells (thyrotrophs), and is a useful marker in classification of pituitary tumors.1-5 

  1. Batanero E, et al. The neural and neuro-endocrine component of the human thymus. II. Hormone immunoreactivity. Brain Behav Immun. 1992; 6:249-64.
  2. Sanno N, et al. GH and PRL gene expression by nonradioisotopic in situ hybridization in TSH-secreting pituitary adenomas. J Clin Endocrinol Metab. 1995; 80:2518-22.
  3. La Rosa S, et al. Detection of gonadotropin-releasing hormone receptor in normal human pituitary cells and pituitary adenomas using immunohistochemistry. Virchows Arch. 2000; 437:264-9.
  4. Kuzuya N, et al. Endocrine and immunohistochemical studies on thyrotropin (TSH)-secreting pituitary adenomas: responses of TSH, alpha-subunit, and growth hormone to hypothalamic releasing hormones and their distribution in adenoma cells. J Clin Endocrinol Metab. 1990; 71:1103-11.
  5. Clore JN, et al. Thyrotropin-induced hyperthyroidism: evidence for a common progenitor stem cell. Am J Med Sci. 1988; 295:3-5.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: pituitary
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate211A-14
0.5 mL concentrate211A-15
1 mL concentrate211A-16
1 mL predilute211A-17
7 mL predilute211A-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate211A-14
0.5 mL concentrate211A-15
1 mL concentrate211A-16
1 mL predilute211A-17
7 mL predilute211A-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate211A-14
0.5 mL concentrate211A-15
1 mL concentrate211A-16
1 mL predilute211A-17
7 mL predilute211A-18

For research use only (RUO) in Japan

0.1 mL concentrate211A-14-RUO
0.5 mL concentrate211A-15-RUO
1 mL concentrate211A-16-RUO
1 mL predilute211A-17-RUO
7 mL predilute211A-18-RUO

 

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