Follicular variant of papillary thyroid carcinoma is labelled by thyroid peroxidase antibody.
Thyroid Peroxidase (EP159) Rabbit Monoclonal Antibody
Specialties: Head/Neck Pathology
Updated: 2017-05-24 08:46:09
Thyroid peroxidase (TPO) is a thyroid-specific enzyme involved in thyroid hormone synthesis. TPO can be found in normal thyroid and thyroid carcinoma of papillary and follicular type. Studies indicate that TPO is a useful marker for the differentiation of benign and malignant thyroid neoplasms.1-3
- Yousaf U, et al. Immunohistochemical staining for thyroid peroxidase (TPO) of needle core biopsies in the diagnosis of scintigraphically cold thyroid nodules. Clin Endocrinol (Oxf). 2005; 68:996-1001.
- Savin S, et al. Thyroid peroxidase and galectin-3 immunostaining in differentiated thyroid carcinoma with clinicopathologic correlation. Hum Pathol. 2008; 39:1656-63.
- Paunovic I, et al. Combined immunohistochemistry for thyroid peroxidase, galectin-3, CK19 and HBME-1 in differential diagnosis of thyroid tumors. APMIS. 2012; 120:368-79.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: thyroid, papillary thyroid carcinoma
- Dilution Range: 1:25-1:100*
Package Inserts
IFU
- IVD Rev. 3.0 (CMC40931030)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 409R-14 |
| 0.5 mL concentrate | 409R-15 |
| 1 mL concentrate | 409R-16 |
| 1 mL predilute | 409R-17 |
| 7 mL predilute | 409R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 409R-14 |
| 0.5 mL concentrate | 409R-15 |
| 1 mL concentrate | 409R-16 |
| 1 mL predilute | 409R-17 |
| 7 mL predilute | 409R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 409R-14 |
| 0.5 mL concentrate | 409R-15 |
| 1 mL concentrate | 409R-16 |
| 1 mL predilute | 409R-17 |
| 7 mL predilute | 409R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 409R-14-RUO |
| 0.5 mL concentrate | 409R-15-RUO |
| 1 mL concentrate | 409R-16-RUO |
| 1 mL predilute | 409R-17-RUO |
| 7 mL predilute | 409R-18-RUO |
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