GLUT1 Rabbit Polyclonal Antibody
Specialties: Cytopathology Pulmonary Pathology
Glucose transporter type I (GLUT1), a prototype member of the GLUT superfamily, is a membrane-associated, erythrocyte glucose transport protein. It is a major glucose transporter in the mammalian blood-brain barrier, and also mediates glucose transport in endothelial cells of the vasculature, adipose tissue, and cardiac muscle. GLUT1 is detectable in many human tissues including those of colon, lung, stomach, and breast. GLUT1 is overexpressed in malignant cells and in a variety of tumors that include mesothelioma and colon carcinoma. Immunohistochemical detection of GLUT1 has been shown to be absent in reactive mesothelium but present in malignant mesothelioma.1,2 Anti-GLUT1 is also useful in distinguishing benign endometrial hyperplasia from atypical endometrial hyperplasia and adenocarcinoma.
- Younes, M et al. "Wide expression of the human erythrocyte glucose transporter Glut1 in human cancers." Cancer research vol. 56,5 (1996): 1164-7.
- Kato, Yasufumi et al. "Immunohistochemical detection of GLUT-1 can discriminate between reactive mesothelium and malignant mesothelioma." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc vol. 20,2 (2007): 215-20.
Specifications
- Reactivity: paraffin
- Control: Colorectal carcinoma (Membranous); Mesothelioma (Membranous)
- Dilution Range: 1:50-1:200 *
Package Inserts
IFU
- IVD Rev. 5.0 (CMC35511050)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 355A-14 |
| 0.5 mL concentrate | 355A-15 |
| 1.0 mL concentrate | 355A-16 |
| 1.0 mL predilute ready-to-use | 355A-17 |
| 7.0 mL predilute ready-to-use | 355A-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 355A-14 |
| 0.5 mL concentrate | 355A-15 |
| 1.0 mL concentrate | 355A-16 |
| 1.0 mL predilute ready-to-use | 355A-17 |
| 7.0 mL predilute ready-to-use | 355A-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 355A-14 |
| 0.5 mL concentrate | 355A-15 |
| 1.0 mL concentrate | 355A-16 |
| 1.0 mL predilute ready-to-use | 355A-17 |
| 7.0 mL predilute ready-to-use | 355A-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 355A-14-RUO |
| 0.5 mL concentrate | 355A-15-RUO |
| 1.0 mL concentrate (RUO) | 355A-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 355A-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 355A-18-RUO |
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