ALK Protein (ALK-1) Mouse Monoclonal Antibody

ALK Protein
ALK Protein (ALK-1) on lymph node.

ALK Protein (ALK-1) Mouse Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-11-13 11:57:11

Anaplastic lymphoma kinase (ALK) is a novel receptor protein-tyrosine kinase.1 ALK can create a fusion protein with a nuclear protein gene called nucleophosmin (NPM) via the amino terminus of NPM and the catalytic domain of ALK.2 The product of this fusion protein is oncogenic.1 Studies have found this chromosomal translocation in most anaplastic large-cell non-Hodgkin's lymphomas, making ALK a good marker for anaplastic large cell lymphomas.2

  1. Iwahara T, et al. Oncogene. 1997; 14:439-49.
  2. Morris SW. Science. 1994; 263:1281-4.

Specifications


  • Reactivity: paraffin
  • Control: Anaplastic large cell lymphoma (Cytoplasmic, Nuclear)
  • Dilution Range: 1:25-1:100 *

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate204M-14
0.5 mL concentrate204M-15
1 mL concentrate204M-16
1 mL predilute204M-17
7 mL predilute204M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate204M-14
0.5 mL concentrate204M-15
1 mL concentrate204M-16
1 mL predilute204M-17
7 mL predilute204M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate204M-14
0.5 mL concentrate204M-15
1 mL concentrate204M-16
1 mL predilute204M-17
7 mL predilute204M-18

For research use only (RUO) in Japan

0.1 mL concentrate204M-14-RUO
0.5 mL concentrate204M-15-RUO
1 mL concentrate204M-16-RUO
1 mL predilute204M-17-RUO
7 mL predilute204M-18-RUO

 

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