CD4 is a 55kD glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It was originally known as leu-3 and T4 before being renamed in 1984. Anti-CD4 is used in the immunophenotyping of reactive lymphocytes and lymphoproliferative disorders. The majority of peripheral T cell lymphomas are derived from the helper T cell subset so that most post-thymic T cell neoplasms are CD4+ CD8-. As with other T cell antigens, CD4 may be aberrantly deleted in neoplastic T cells so that the evaluation of such tumors requires the application of a panel of markers in order to identify tumors with such anomalous antigenic expression.
|0.1 ml concentrated||104R-14|
|0.5 ml concentrated||104R-15|
|1 ml concentrated||104R-16|
|1 ml prediluted||104R-17|
|7 ml prediluted||104R-18|
|5 Positive Control Slides ||104S||
||Instructions for Use
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