FOXM1 (EP372) Rabbit Monoclonal Antibody

FOXM1
Tonsil stained with anti-FOXM1

FOXM1 (EP372) Rabbit Monoclonal Antibody

Updated: 2017-05-24 08:46:09

Forkhead box protein M1 (FOXM1) is a major oncogenic transcription factor responsible for regulating genes involved in G1-S and G2-M cell cycle transitions into DNA replication and mitosis, respectively. FOXM1 is broadly distributed during embryonic development, but restricted to progenitor and proliferating cells in mature tissues.

FOXM1 has been implicated in tumorigenesis, facilitating tumor proliferation, angiogenesis and migration. Genome wide microarray studies consistently demonstrated FOXM1 upregulation in many solid malignancies. FOXM1 overexpression is associated with chemotherapeutic resistance and poorer patient prognosis. Recent studies revealed close correlation between FOXM1 expression and HER2 status in breast cancers.

Specifications


  • Dilution Range: 1:20*

Package Inserts


IFU:
IFU included with product

SDS:
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Ordering Information

For research use only (RUO) in USA

0.1 mL concentrateAC-0323RUO
1 mL concentrateAC-0323RUOC

This product is not available in Canada

For research use only (RUO) in the EU

0.1 mL concentrateAC-0323RUO
1 mL concentrateAC-0323RUOC

For research use only (RUO) in Japan

0.1 mL concentrateAC-0323RUO
1 mL concentrateAC-0323RUOC

 

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