PAX5 (EP156) Rabbit Monoclonal Antibody
PAX5 is a B-cell lineage specific activator protein (BSAP) that is essential for maintaining the identity and function of mature B cells during late B lymphopoiesis. It also plays a role in neural development and spermatogenesis. PAX5 is expressed in pro-, pre-, and mature B cells, and it is expressed in the vast majority of B-cell malignancies. Anti-PAX5 is a specific marker for the B-cell lineage. PAX5 is thus useful with a panel of antibodies for the identification of cellular origin of undifferentiated tumors. The expression of PAX5 in endocrine tumors has been shown to be high in Merkel cell carcinoma and small cell carcinoma, but not carcinoid tumor. PAX5 is also a marker for neuroendocrine carcinomas.
Specifications
- Reactivity: paraffin
- Visualization: nuclear
- Control: tonsil, B-lymphoblastic neoplasm
- Dilution Range: 1:100 - 1:200*
Package Inserts
IFU:
IFU included with product
SDS:
Download your SDS
Ordering Information
For in vitro diagnostic (IVD) use in USA
1 mL concentrate | AC-0158 |
0.1 mL concentrate | AC-0158A |
This product is not available in Canada
For in vitro diagnostic (IVD) use in Europe
1 mL concentrate | AC-0158 |
0.1 mL concentrate | AC-0158A |
For research use only (RUO) in Japan
1 mL concentrate | AC-0158 |
0.1 mL concentrate | AC-0158A |
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