Granzyme B (EP230) Rabbit Monoclonal Antibody
Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas in conjunction with CD56.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic granule
- Control: tonsil, Hodgkin's lymphoma
- Dilution Range: 1:20*
Package Inserts
IFU:
IFU included with product
SDS:
Download your SDS
Ordering Information
For in vitro diagnostic (IVD) use in USA
1 mL concentrate | AC-0213 |
0.1 mL concentrate | AC-0213A |
This product is not available in Canada
For in vitro diagnostic (IVD) use in Europe
1 mL concentrate | AC-0213 |
0.1 mL concentrate | AC-0213A |
For research use only (RUO) in Japan
1 mL concentrate | AC-0213 |
0.1 mL concentrate | AC-0213A |
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