CD30 (EP154) Rabbit Monoclonal Antibody

CD30

CD30 (EP154) Rabbit Monoclonal Antibody

Updated: 2017-05-24 08:46:09

CD30, TNF-receptor superfamily member, is a receptor for TNFSF8/CD30L. TRAF2 and TRAF5 can interact with this receptor and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and it also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. The CD30 antibody labels activated B and T cells. It has been useful in identifying Hodgkin's lymphoma, anaplastic large cell lymphomas (ALCL) and primary cutaneous CD30+ T-cell lymphoproliferative disorders. In non-lymphoid malignancies, CD30 reactivity has been reported in embryonal carcinomas (ECs), seminomas, and hepatocellular carcinomas.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: tonsil, Hodgkin's lymphoma
  • Dilution Range: 1:100 - 1:200*

Package Inserts


IFU:
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SDS:
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Ordering Information

For in vitro diagnostic (IVD) use in USA

1 mL concentrateAC-0141
0.1 mL concentrateAC-0141A

This product is not available in Canada

For in vitro diagnostic (IVD) use in Europe

1 mL concentrateAC-0141
0.1 mL concentrateAC-0141A

For research use only (RUO) in Japan

1 mL concentrateAC-0141
0.1 mL concentrateAC-0141A

 

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