Cytokeratin 14 (LL002) Mouse Monoclonal Antibody

Cytokeratin 14
In the salivary gland, contractile myoepithelial cells are highlighted by anti-cytokeratin14.

Cytokeratin 14 (LL002) Mouse Monoclonal Antibody

Specialties: Anatomic Pathology

Updated: 2017-05-24 08:46:09

Cytokeratin 14 is a member of the Type I family of cytokeratins and is generally expressed in the basal cell layer of squamous epithelium.  The cytokeratin 14 protein forms a heterotetramer with homodimers of cytokeratin 5 to contribute to the structural integrity of the intracellular cytoskeletal network.1 Anti-cytokeratin 14 has immunohistochemical utility as an aid in distinguishing squamous cell carcinomas from other tumors of epithelial origin.2

  1. Moll R, et al. The human keratins: biology and pathology. Histochem Cell Biol. 2008; 129:705-33.
  2. Chu PG, et al. Cytokeratin 14 expression in epithelial neoplasms: a survey of 435 cases with emphasis on its value in differentiating squamous cell carcinomas from other epithelial tumours. Histopathology. 2001; 39:9-16.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: squamous cell carcinoma
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate314M-14
0.5 mL concentrate314M-15
1 mL concentrate314M-16
1 mL predilute314M-17
7 mL predilute314M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate314M-14
0.5 mL concentrate314M-15
1 mL concentrate314M-16
1 mL predilute314M-17
7 mL predilute314M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate314M-14
0.5 mL concentrate314M-15
1 mL concentrate314M-16
1 mL predilute314M-17
7 mL predilute314M-18

For research use only (RUO) in Japan

0.1 mL concentrate314M-14-RUO
0.5 mL concentrate314M-15-RUO
1 mL concentrate314M-16-RUO
1 mL predilute314M-17-RUO
7 mL predilute314M-18-RUO

 

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