CD74 (LN2) Mouse Monoclonal Antibody

CD74
Germinal center cells and paracortical T-zone cells are positive in cytoplasmic staining pattern for CD74 antibody.

CD74 (LN2) Mouse Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas but rarely T-cell lymphomas. It stains the cell membrane but a paranuclear globular labeling is also noted. It is a useful addition to the lymphoma phenotyping panel. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma from malignant fibrous histiocytoma, as well as small cell lung carcinomas from non-small cell lung carcinomas.1-8  

  1. Chan JKC, et al. Histopathology. 1994; 25:517-536.
  2. Kasaian MT, et al. Proc Soc Exp Bio Med. 1991; 197:226-241.
  3. Jones NH, et al. Nature. 1986; 323:346-349.
  4. Lazova R, et al. Cancer. 1997; 79:2115-24.
  5. Ioachim HL, et al. Am J SurgPathol. 1996; 20:64-71.
  6. Tang X, et al. Pathol Int. 1995; 45:34-44.
  7. Ohsawa M, et al. J ClinPathol. 1994; 47:928-32.
  8. Ross CW, et al. Cancer. 1992; 70:2517-23.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic and membranous
  • Control: tonsil, lymph node
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate174M-14
0.5 mL concentrate174M-15
1 mL concentrate174M-16
1 mL predilute174M-17
7 mL predilute174M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate174M-14
0.5 mL concentrate174M-15
1 mL concentrate174M-16
1 mL predilute174M-17
7 mL predilute174M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate174M-14
0.5 mL concentrate174M-15
1 mL concentrate174M-16
1 mL predilute174M-17
7 mL predilute174M-18

For research use only (RUO) in Japan

0.1 mL concentrate174M-14-RUO
0.5 mL concentrate174M-15-RUO
1 mL concentrate174M-16-RUO
1 mL predilute174M-17-RUO
7 mL predilute174M-18-RUO

 

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