CD74 (LN2) Mouse Monoclonal Antibody
Specialties: Hematopathology
Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas but rarely T-cell lymphomas. It stains the cell membrane but a paranuclear globular labeling is also noted. It is a useful addition to the lymphoma phenotyping panel. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma from malignant fibrous histiocytoma, as well as small cell lung carcinomas from non-small cell lung carcinomas.1-8
- Chan JKC, et al. Histopathology. 1994; 25:517-536.
- Kasaian MT, et al. Proc Soc Exp Bio Med. 1991; 197:226-241.
- Jones NH, et al. Nature. 1986; 323:346-349.
- Lazova R, et al. Cancer. 1997; 79:2115-24.
- Ioachim HL, et al. Am J SurgPathol. 1996; 20:64-71.
- Tang X, et al. Pathol Int. 1995; 45:34-44.
- Ohsawa M, et al. J ClinPathol. 1994; 47:928-32.
- Ross CW, et al. Cancer. 1992; 70:2517-23.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic and membranous
- Control: tonsil, lymph node
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC17421040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 174M-14 |
| 0.5 mL concentrate | 174M-15 |
| 1 mL concentrate | 174M-16 |
| 1 mL predilute | 174M-17 |
| 7 mL predilute | 174M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 174M-14 |
| 0.5 mL concentrate | 174M-15 |
| 1 mL concentrate | 174M-16 |
| 1 mL predilute | 174M-17 |
| 7 mL predilute | 174M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 174M-14 |
| 0.5 mL concentrate | 174M-15 |
| 1 mL concentrate | 174M-16 |
| 1 mL predilute | 174M-17 |
| 7 mL predilute | 174M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 174M-14-RUO |
| 0.5 mL concentrate | 174M-15-RUO |
| 1 mL concentrate | 174M-16-RUO |
| 1 mL predilute | 174M-17-RUO |
| 7 mL predilute | 174M-18-RUO |
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