CD61 (2f2) Mouse Monoclonal Antibody

CD61
Megakaryocytes are strongly highlighted in a cytoplasmic staining reaction.

CD61 (2f2) Mouse Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

CD61 also known as integrin beta chain beta 3 (ITGB3) is an integrin cell-surface protein associated with cellular adhesion and cell-surface mediated signaling. Immunohistochemical staining for CD61 can be useful in evaluating normal and abnormal megakaryocytes, which can aide in the identification of some hematopoietic malignancies. Anti-CD61 reactivity is also seen in platelets, osteoclasts and macrophages.1-4

  1. Thiele J, et al. An immunomorphometric study on megakaryocyte precursor cells in bone marrow tissue from patients with chronic myeloid leukemia (CML). Eur J Haematol. 1990; 44:63-70.
  2. Thiele J, et al. Megakaryocyte precursors (pro- and megakaryoblasts) in bone marrow tissue from patients with reactive thrombocytosis, polycythemia vera and primary (essential) thrombocythemia. An immunomorphometric study. Virchows Archiv B Cell Pathol. 1990; 58:295-302.
  3. Fox SB, et al. Megakaryocytes in myelodysplasia: an immunohistochemical study on bone marrow trephines. Histopathology. 1990; 17:69-74.
  4. Thiele J, et al. Megakaryocyte precursors (promegakaryoblasts and megakaryoblasts) in the normal human bone marrow. An immunohistochemical and morphometric study on routinely processed trephine biopsies. Anal Quant Histol. 1990; 12:285-9.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: bone marrow
  • Dilution Range: 1:25-1:100*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate161M-14
0.5 mL concentrate161M-15
1 mL concentrate161M-16
1 mL predilute161M-17
7 mL predilute161M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate161M-14
0.5 mL concentrate161M-15
1 mL concentrate161M-16
1 mL predilute161M-17
7 mL predilute161M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate161M-14
0.5 mL concentrate161M-15
1 mL concentrate161M-16
1 mL predilute161M-17
7 mL predilute161M-18

For research use only (RUO) in Japan

0.1 mL concentrate161M-14-RUO
0.5 mL concentrate161M-15-RUO
1 mL concentrate161M-16-RUO
1 mL predilute161M-17-RUO
7 mL predilute161M-18-RUO

 

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