Cell Marque Portfolio

CD61 (2f2)

Mouse Monoclonal


CD61 also known as integrin beta chain beta 3 (ITGB3) is an integrin cell-surface protein associated with cellular adhesion and cell-surface mediated signaling. Immunohistochemical staining for CD61 can be useful in evaluating normal and abnormal megakaryocytes, which can aide in the identification of some hematopoietic malignancies. Anti-CD61 reactivity is also seen in platelets, osteoclasts and macrophages.1-4

Specialties: Hematopathology

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: bone marrow
  • Isotype: IgG1
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

References


  1. Thiele J, et al. An immunomorphometric study on megakaryocyte precursor cells in bone marrow tissue from patients with chronic myeloid leukemia (CML). Eur J Haematol. 1990; 44:63-70.
  2. Thiele J, et al. Megakaryocyte precursors (pro- and megakaryoblasts) in bone marrow tissue from patients with reactive thrombocytosis, polycythemia vera and primary (essential) thrombocythemia. An immunomorphometric study. Virchows Archiv B Cell Pathol. 1990; 58:295-302.
  3. Fox SB, et al. Megakaryocytes in myelodysplasia: an immunohistochemical study on bone marrow trephines. Histopathology. 1990; 17:69-74.
  4. Thiele J, et al. Megakaryocyte precursors (promegakaryoblasts and megakaryoblasts) in the normal human bone marrow. An immunohistochemical and morphometric study on routinely processed trephine biopsies. Anal Quant Histol. 1990; 12:285-9.

Last updated: 2017-05-24 08:46:09

CD61
Megakaryocytes are strongly highlighted in a cytoplasmic staining reaction.

Mouse over to zoom, use scroll wheel to zoom in/out

Tap image once to activate zoom lens


Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: bone marrow
  • Isotype: IgG1
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

References


  1. Thiele J, et al. An immunomorphometric study on megakaryocyte precursor cells in bone marrow tissue from patients with chronic myeloid leukemia (CML). Eur J Haematol. 1990; 44:63-70.
  2. Thiele J, et al. Megakaryocyte precursors (pro- and megakaryoblasts) in bone marrow tissue from patients with reactive thrombocytosis, polycythemia vera and primary (essential) thrombocythemia. An immunomorphometric study. Virchows Archiv B Cell Pathol. 1990; 58:295-302.
  3. Fox SB, et al. Megakaryocytes in myelodysplasia: an immunohistochemical study on bone marrow trephines. Histopathology. 1990; 17:69-74.
  4. Thiele J, et al. Megakaryocyte precursors (promegakaryoblasts and megakaryoblasts) in the normal human bone marrow. An immunohistochemical and morphometric study on routinely processed trephine biopsies. Anal Quant Histol. 1990; 12:285-9.

Package Inserts

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate 161M-14
0.5 mL concentrate 161M-15
1 mL concentrate 161M-16
1 mL predilute 161M-17
7 mL predilute 161M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate 161M-14
0.5 mL concentrate 161M-15
1 mL concentrate 161M-16
1 mL predilute 161M-17
7 mL predilute 161M-18

For in vitro diagnostic (IVD) use in the EU

0.1 mL concentrate 161M-14
0.5 mL concentrate 161M-15
1 mL concentrate 161M-16
1 mL predilute 161M-17
7 mL predilute 161M-18

For research use only (RUO) in Japan

0.1 mL concentrate 161M-14-RUO
0.5 mL concentrate 161M-15-RUO
1 mL concentrate 161M-16-RUO
1 mL predilute 161M-17-RUO
7 mL predilute 161M-18-RUO

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: bone marrow
  • Isotype: IgG1
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download Package Insert

Select revision:


Keycode Specific Package Insert

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

Download SDS

References


  1. Thiele J, et al. An immunomorphometric study on megakaryocyte precursor cells in bone marrow tissue from patients with chronic myeloid leukemia (CML). Eur J Haematol. 1990; 44:63-70.
  2. Thiele J, et al. Megakaryocyte precursors (pro- and megakaryoblasts) in bone marrow tissue from patients with reactive thrombocytosis, polycythemia vera and primary (essential) thrombocythemia. An immunomorphometric study. Virchows Archiv B Cell Pathol. 1990; 58:295-302.
  3. Fox SB, et al. Megakaryocytes in myelodysplasia: an immunohistochemical study on bone marrow trephines. Histopathology. 1990; 17:69-74.
  4. Thiele J, et al. Megakaryocyte precursors (promegakaryoblasts and megakaryoblasts) in the normal human bone marrow. An immunohistochemical and morphometric study on routinely processed trephine biopsies. Anal Quant Histol. 1990; 12:285-9.
Request More Information