CD45RO (UCHL-1) Mouse Monoclonal Antibody

CD45RO
CD45RO (UCHL-1) on tonsil.

CD45RO (UCHL-1) Mouse Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

Anti-CD45RO labels an isoform of the CD45 antigen also known as leukocyte common antigen. Anti-CD45RO reacts with thymocytes, mature activated T-cells, and a subpopulation of resting T-cells while showing no reactivity with B-cells, making this antibody helpful in identifying T-cell neoplasms.1-7

  1. Hall PA, et al. New marker of B lymphocytes, MB2: comparison with other lymphocyte subset markers active in conventionally processed tissue sections. J Clin Pathol. 1987; 40:151-6.
  2. Smith SH, et al. Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1. Immunology 1986; 58:63-70.
  3. Cabeçadas JM, et al. Phenotyping of T-cell lymphomas in paraffin sections--which antibodies? Histopathology. 1991; 19:419-24.
  4. Tworek JA, et al. Flow cytometric and immunohistochemical analysis of small lymphocytic lymphoma, mantle cell lymphoma, and plasmacytoid small lymphocytic lymphoma. Am J Clin Pathol. 1998; 110:582-9.
  5. Falini B, et al. Variable expression of leucocyte-common (CD45) antigen in CD30 (Ki1)-positive anaplastic large-cell lymphoma: implications for the differential diagnosis between lymphoid and nonlymphoid malignancies. Hum Pathol. 1990; 21:624-9.
  6. Koch AE, et al. Distribution of CD45RA and CD45RO T-lymphocyte subsets in rheumatoid arthritis synovial tissue. J Clin Immunol. 1990; 10:192-9.
  7. Ritter JH, et al. Paraffin section immunohistochemistry as an adjunct to morphologic analysis in the diagnosis of cutaneous lymphoid infiltrates. J Cutan Pathol. 1994; 21:481-93.

Specifications


  • Reactivity: paraffin
  • Visualization: membranous, nuclear
  • Control: tonsil
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate147M-94
0.5 mL concentrate147M-95
1 mL concentrate147M-96
1 mL predilute147M-97
7 mL predilute147M-98

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate147M-94
0.5 mL concentrate147M-95
1 mL concentrate147M-96
1 mL predilute147M-97
7 mL predilute147M-98

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate147M-94
0.5 mL concentrate147M-95
1 mL concentrate147M-96
1 mL predilute147M-97
7 mL predilute147M-98

For research use only (RUO) in Japan

0.1 mL concentrate147M-94-RUO
0.5 mL concentrate147M-95-RUO
1 mL concentrate147M-96-RUO
1 mL predilute147M-97-RUO
7 mL predilute147M-98-RUO

 

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