Cell Marque Portfolio

CD45 (LCA) (2B11 & PD7/26)

Mouse Monoclonal


Anti-CD45 (anti-leukocyte common antigen) is routinely used to aid the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphoma is suspected by the morphological or clinical data. It is a highly specific antibody, therefore a positive result is highly indicative of hematolymphoid origin. Certain types of hematolymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors.1-8

Specialties: Hematopathology

Specifications


  • Reactivity: paraffin
  • Visualization: membranous
  • Control: tonsil, lymph node, lymphoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/8min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C

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References


  1. Mason, DY. Am J Pathol. 1987; 128:1-4.
  2. Hall PA, et al. Histopathology. 1988; 13:149-160.
  3. Kurtin PJ, et al. Hum Path. 1985; 16:353-365.
  4. Maluf HM, et al. Mod Pathol. 1995; 8:155-9.
  5. Caballero T, et al. J Clin Pathol. 1995; 48:743-8.
  6. Vasef MA, et al. Am J Clin Pathol. 1997; 108:54-9.
  7. Saxena A, et al. Am J Clin Pathol. 1999; 112:495-512.
  8. Kraus MD, et al. Am J Surg Pathol. 2000; 24:1068-78.

Last updated: 2016-01-07 14:13:45

CD45 (LCA)
CD45 (LCA) (2B11 & PD7/26) on tonsil.

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Specifications


  • Reactivity: paraffin
  • Visualization: membranous
  • Control: tonsil, lymph node, lymphoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/8min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C

References


  1. Mason, DY. Am J Pathol. 1987; 128:1-4.
  2. Hall PA, et al. Histopathology. 1988; 13:149-160.
  3. Kurtin PJ, et al. Hum Path. 1985; 16:353-365.
  4. Maluf HM, et al. Mod Pathol. 1995; 8:155-9.
  5. Caballero T, et al. J Clin Pathol. 1995; 48:743-8.
  6. Vasef MA, et al. Am J Clin Pathol. 1997; 108:54-9.
  7. Saxena A, et al. Am J Clin Pathol. 1999; 112:495-512.
  8. Kraus MD, et al. Am J Surg Pathol. 2000; 24:1068-78.

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 145M-94
0.5 ml, concentrate 145M-95
1 ml, concentrate 145M-96
1 ml, predilute 145M-97
7 ml, predilute 145M-98
25 ml, predilute 145M-90

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 145M-94
0.5 ml, concentrate 145M-95
1 ml, concentrate 145M-96
1 ml, predilute 145M-97
7 ml, predilute 145M-98
25 ml, predilute 145M-90

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 145M-94
0.5 ml, concentrate 145M-95
1 ml, concentrate 145M-96
1 ml, predilute 145M-97
7 ml, predilute 145M-98
25 ml, predilute 145M-90

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 145M-94 (RUO)
0.5 ml, concentrate 145M-95 (RUO)
1 ml, concentrate 145M-96 (RUO)
1 ml, predilute 145M-97 (RUO)
7 ml, predilute 145M-98 (RUO)
25 ml, predilute 145M-90 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: membranous
  • Control: tonsil, lymph node, lymphoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/8min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

References


  1. Mason, DY. Am J Pathol. 1987; 128:1-4.
  2. Hall PA, et al. Histopathology. 1988; 13:149-160.
  3. Kurtin PJ, et al. Hum Path. 1985; 16:353-365.
  4. Maluf HM, et al. Mod Pathol. 1995; 8:155-9.
  5. Caballero T, et al. J Clin Pathol. 1995; 48:743-8.
  6. Vasef MA, et al. Am J Clin Pathol. 1997; 108:54-9.
  7. Saxena A, et al. Am J Clin Pathol. 1999; 112:495-512.
  8. Kraus MD, et al. Am J Surg Pathol. 2000; 24:1068-78.
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