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CD45 (LCA) (2B11 & PD7/26)

Mouse Monoclonal


Anti-CD45 (anti-leukocyte common antigen) is routinely used to aid the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphoma is suspected by the morphological or clinical data. It is a highly specific antibody, therefore a positive result is highly indicative of hematolymphoid origin. Certain types of hematolymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors.1-8

Specialties: Hematopathology

Specifications


  • Reactivity: paraffin
  • Visualization: membranous
  • Control: tonsil, lymph node, lymphoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/8min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C

Package Inserts


IFU SDS

References


  1. Mason, DY. Am J Pathol. 1987; 128:1-4.
  2. Hall PA, et al. Histopathology. 1988; 13:149-160.
  3. Kurtin PJ, et al. Hum Path. 1985; 16:353-365.
  4. Maluf HM, et al. Mod Pathol. 1995; 8:155-9.
  5. Caballero T, et al. J Clin Pathol. 1995; 48:743-8.
  6. Vasef MA, et al. Am J Clin Pathol. 1997; 108:54-9.
  7. Saxena A, et al. Am J Clin Pathol. 1999; 112:495-512.
  8. Kraus MD, et al. Am J Surg Pathol. 2000; 24:1068-78.

Last updated: 2017-05-24 08:46:09

CD45 (LCA)
CD45 (LCA) (2B11 & PD7/26) on tonsil.

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Specifications


  • Reactivity: paraffin
  • Visualization: membranous
  • Control: tonsil, lymph node, lymphoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/8min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C

References


  1. Mason, DY. Am J Pathol. 1987; 128:1-4.
  2. Hall PA, et al. Histopathology. 1988; 13:149-160.
  3. Kurtin PJ, et al. Hum Path. 1985; 16:353-365.
  4. Maluf HM, et al. Mod Pathol. 1995; 8:155-9.
  5. Caballero T, et al. J Clin Pathol. 1995; 48:743-8.
  6. Vasef MA, et al. Am J Clin Pathol. 1997; 108:54-9.
  7. Saxena A, et al. Am J Clin Pathol. 1999; 112:495-512.
  8. Kraus MD, et al. Am J Surg Pathol. 2000; 24:1068-78.

Package Inserts

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

25 mL predilute 145M-90
0.1 mL concentrate 145M-94
0.5 mL concentrate 145M-95
1 mL concentrate 145M-96
1 mL predilute 145M-97
7 mL predilute 145M-98

For in vitro diagnostic (IVD) use in Canada

25 mL predilute 145M-90
0.1 mL concentrate 145M-94
0.5 mL concentrate 145M-95
1 mL concentrate 145M-96
1 mL predilute 145M-97
7 mL predilute 145M-98

For in vitro diagnostic (IVD) use in Europe

25 mL predilute 145M-90
0.1 mL concentrate 145M-94
0.5 mL concentrate 145M-95
1 mL concentrate 145M-96
1 mL predilute 145M-97
7 mL predilute 145M-98

For research use only (RUO) in Japan

25 mL predilute 145M-90-RUO
0.1 mL concentrate 145M-94-RUO
0.5 mL concentrate 145M-95-RUO
1 mL concentrate 145M-96-RUO
1 mL predilute 145M-97-RUO
7 mL predilute 145M-98-RUO

 

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Specifications


  • Reactivity: paraffin
  • Visualization: membranous
  • Control: tonsil, lymph node, lymphoma
  • Isotype: IgG1/k
  • Dilution Range: 1:100-1:500*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana OptiView
    OV/CC1(32min)/8min @ 37°C
  • Ventana ultraView
    UV/CC1M/16min @ 37°C

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References


  1. Mason, DY. Am J Pathol. 1987; 128:1-4.
  2. Hall PA, et al. Histopathology. 1988; 13:149-160.
  3. Kurtin PJ, et al. Hum Path. 1985; 16:353-365.
  4. Maluf HM, et al. Mod Pathol. 1995; 8:155-9.
  5. Caballero T, et al. J Clin Pathol. 1995; 48:743-8.
  6. Vasef MA, et al. Am J Clin Pathol. 1997; 108:54-9.
  7. Saxena A, et al. Am J Clin Pathol. 1999; 112:495-512.
  8. Kraus MD, et al. Am J Surg Pathol. 2000; 24:1068-78.
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