CD34 (EP88) Rabbit Monoclonal Antibody
Specialties: Hematopathology
CD34 is a cell surface glycophosphoprotein expressed on human hematopoietic progenitor cells, vascular endothelial cells, and embryonic fibroblasts.1 The exact function of CD34 has not yet been determined, though studies have found it may enhance proliferation and block differentiation of stem or progenitor cells, and promote lymphocyte adhesion to vascular endothelium in lymphoid tissues.2 CD34 expression has also been observed in some gastrointestinal stromal tumors (GIST).3
- Torlakovic G, et al. CD34/QBEND10 immunostaining in the bone marrow trephine biopsy: a study of CD34-positive mononuclear cells and megakaryocytes. Arch Pathol Lab Med. 2002; 126:823-8.
- Nielsen JS, et al. Novel functions of the CD34 family. J Cell Sci. 2008; 121: 3683-92.
- Kisluk J, et al. Immunohistochemical diagnosis of gastrointestinal stromal tumors - an analysis of 80 cases from 2004 to 2010. Adv. Clin Exp Med. 2013; 22:33-9.
Specifications
- Reactivity: paraffin
- Visualization: membranous
- Control: tonsil, placenta
- Dilution Range: 1:50-1:200*
Package Inserts
IFU
- IVD Rev. 2.0 (CMC13431020)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 134R-14 |
| 0.5 mL concentrate | 134R-15 |
| 1 mL concentrate | 134R-16 |
| 1 mL predilute | 134R-17 |
| 7 mL predilute | 134R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 134R-14 |
| 0.5 mL concentrate | 134R-15 |
| 1 mL concentrate | 134R-16 |
| 1 mL predilute | 134R-17 |
| 7 mL predilute | 134R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 134R-14 |
| 0.5 mL concentrate | 134R-15 |
| 1 mL concentrate | 134R-16 |
| 1 mL predilute | 134R-17 |
| 7 mL predilute | 134R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 134R-14-RUO |
| 0.5 mL concentrate | 134R-15-RUO |
| 1 mL concentrate | 134R-16-RUO |
| 1 mL predilute | 134R-17-RUO |
| 7 mL predilute | 134R-18-RUO |
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