Cytokeratin 5 & 6 (EP24 & EP67) Rabbit Monoclonal Primary Antibody

Cytokeratin 5 & 6
Cytokeratin 5 & 6 Cocktail (EP24 & EP67) on esophageal squamous cell carcinoma.

Cytokeratin 5 & 6 (EP24 & EP67) Rabbit Monoclonal Primary Antibody

Specialties: Anatomic Pathology Cytopathology

Updated: 2019-04-17 15:04:57

Twenty identified cytokeratins make up a complex family of intermediate filaments.1 Cytokeratin 5 (58kDa) & cytokeratin 6 (56kDa) are type II high molecular weight keratins that are expressed in a broad range of normal tissues including breast, prostate, mesothelium, skin and esophagus.1-3 Anti-Cytokeratin 5 & 6 is a useful immunohistochemical marker in the identification of mesothelioma and lung squamous cell carcinoma.1

  1. Ordóñez NG. Value of cytokeratin 5/6 immunostaining in distinguishing epithelial mesothelioma of the pleura from lung adenocarcinoma. Am J Surg Pathol. 1998; 22:1215-21
  2. Takahashi K, et al. Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms. J Biol Chem. 1995; 270:18581-92.
  3. Lersch R, et al. Isolation, sequence, and expression of a human keratin K5 gene: transcriptional regulation of keratins and insights into pairwise control. Mol Cell Biol. 1989; 9:3685-97.

Specifications


  • Reactivity: paraffin
  • Control: Mesothelioma (Cytoplasmic); Prostate (Cytoplasmic); Lung squamous cell carcinoma (Cytoplasmic)
  • Dilution Range: 1:25-1:100 *

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate356R-14
0.5 mL concentrate356R-15
1.0 mL concentrate356R-16
1.0 mL predilute ready-to-use356R-17
7.0 mL predilute ready-to-use356R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate356R-14
0.5 mL concentrate356R-15
1.0 mL concentrate356R-16
1.0 mL predilute ready-to-use356R-17
7.0 mL predilute ready-to-use356R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate356R-14
0.5 mL concentrate356R-15
1.0 mL concentrate356R-16
1.0 mL predilute ready-to-use356R-17
7.0 mL predilute ready-to-use356R-18

For research use only (RUO) in Japan

0.1 mL concentrate (RUO)356R-14-RUO
0.5 mL concentrate (RUO)356R-15-RUO
1.0 mL concentrate (RUO)356R-16-RUO
1.0 mL predilute ready-to-use (RUO)356R-17-RUO
7.0 mL predilute ready-to-use (RUO)356R-18-RUO

 

To request information on this product in additional countries, please click the button below.

Request More Information