CD11c (EP157) Rabbit Monoclonal Antibody

CD11c
CD11c (EP157) on Hairy Cell Leukemia.

CD11c (EP157) Rabbit Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

CD11c is an adhesion receptor of the leukocyte function-associated family of molecules. This cell surface antigen is normally expressed on granulocytes, monocytes, natural killer cells, macrophages, and small populations of T- and B-lymphocytes. Anti-CD11c detects a formalin-resistant epitope of CD11c expressed in hairy cell leukemia (HCL). HCL is a distinctive yet uncommon chronic B-cell lymphoproliferative disorder, predominantly involving the bone marrow and spleen. Besides being consistently expressed in HCL, CD11c is rarely detected in lymphomas; such as small lymphocytic lymphoma (SLL), and nodal and extranodal marginal zone lymphoma (MZL).1-3

  1. Johrens K, et al. Pathobiology. 2008; 75:252-256.
  2. Jones G, et al. Br J Hemaetol. 2012; 156:186-195.
  3. Marotta, G et al. Leuk Lymphoma. 2000; 37:145-9.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: hairy cell leukemia, spleen, tonsil
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate111R-14
0.5 mL concentrate111R-15
1 mL concentrate111R-16
1 mL predilute111R-17
7 mL predilute111R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate111R-14
0.5 mL concentrate111R-15
1 mL concentrate111R-16
1 mL predilute111R-17
7 mL predilute111R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate111R-14
0.5 mL concentrate111R-15
1 mL concentrate111R-16
1 mL predilute111R-17
7 mL predilute111R-18

For research use only (RUO) in Japan

0.1 mL concentrate111R-14-RUO
0.5 mL concentrate111R-15-RUO
1 mL concentrate111R-16-RUO
1 mL predilute111R-17-RUO
7 mL predilute111R-18-RUO

 

To request information on this product in additional countries, please click the button below.

Request More Information