CD3 polyclonal antibody stains interfollicular T-cells in a cytoplasmic staining pattern.
CD3 Rabbit Polyclonal Antibody
Specialties: Hematopathology
Updated: 2017-05-24 08:46:09
CD3’s immunohistochemical detection locates the cytoplasmic component of CD3 protein. Anti-CD3 is considered to be a pan-T-cell marker and reacts with an antigen present at the surface and in the cytoplasm of T lymphocytes. Anti-CD3 is widely used for the identification of immature and mature T-cell malignancies.1-8
- Denning SM, et al. Activation of human thymocytes via CD3 and CD2 molecules. In: McMichael AJ, et al. eds. Leucocyte Typing III, White Cell Differentiation Antigens. Oxford-New York-Tokyo. Oxford University Press. 1987; 144-7.
- Beverley PC, et al. Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody. Eur J Immunol. 1981; 11:329-34.
- Clevers H, et al. The transmembrane orientation of the epsilon chain of the TcR/CD3 complex. Eur J Immunol. 1988; 18:705-10.
- Campana D, et al. The cytoplasmic expression of CD3 antigens in normal and malignant cells of the T lymphoid lineage. J Immunol. 1987; 138:648-55.
- Hedvat CV, et al. Application of tissue microarray technology to the study of non-Hodgkin's and Hodgkin's lymphoma. Hum Pathol. 2002; 33:968-74.
- Karube K, et al. Non-B, non-T neoplasms with lymphoblast morphology: further clarification and classification. Am J Surg Pathol. 2003; 27:1366-74.
- Dogan A, et al. Micronodular T-cell/histiocyte-rich large B-cell lymphoma of the spleen: histology, immunophenotype, and differential diagnosis. Am J Surg Pathol. 2003; 27:903-11.
- Axdorph U, et al. T-cell-rich B-cell lymphoma - diagnostic and therapeutic aspects. APMIS. 2002; 110:379-90.
Specifications
- Reactivity: paraffin
- Visualization: membranous
- Control: tonsil
- Dilution Range: 1:100-1:1000*
Package Inserts
IFU
- IVD Rev. 6.0 (CMC10317060)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 25 mL predilute | 103A-70 |
| 0.1 mL concentrate | 103A-74 |
| 0.5 mL concentrate | 103A-75 |
| 1 mL concentrate | 103A-76 |
| 1 mL predilute | 103A-77 |
| 7 mL predilute | 103A-78 |
For in vitro diagnostic (IVD) use in Canada
| 25 mL predilute | 103A-70 |
| 0.1 mL concentrate | 103A-74 |
| 0.5 mL concentrate | 103A-75 |
| 1 mL concentrate | 103A-76 |
| 1 mL predilute | 103A-77 |
| 7 mL predilute | 103A-78 |
For in vitro diagnostic (IVD) use in Europe
| 25 mL predilute | 103A-70 |
| 0.1 mL concentrate | 103A-74 |
| 0.5 mL concentrate | 103A-75 |
| 1 mL concentrate | 103A-76 |
| 1 mL predilute | 103A-77 |
| 7 mL predilute | 103A-78 |
For research use only (RUO) in Japan
| 25 mL predilute | 103A-70-RUO |
| 0.1 mL concentrate | 103A-74-RUO |
| 0.5 mL concentrate | 103A-75-RUO |
| 1 mL concentrate | 103A-76-RUO |
| 1 mL predilute | 103A-77-RUO |
| 7 mL predilute | 103A-78-RUO |
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