CD7 (EP132) Rabbit Monoclonal Antibody

CD7
Rabbit monoclonal CD7 antibody stains cutaneous T-cell lymphoma in a cytoplasmic reaction.

CD7 (EP132) Rabbit Monoclonal Antibody

Specialties: Hematopathology Anatomic Pathology

Updated: 2017-05-24 08:46:09

CD7 antigen is a 40-kDa cell surface glycoprotein that is a member of the immunoglobulin gene superfamily.1,2 While its precise function is not known, it is suggested that CD7 plays a role in T-cell interactions as it is one of the earliest T-cell lineage associated antigens expressed during T-cell ontogeny.2,3 CD7 is expressed in thymocytes, mature peripheral T-cells, natural killer cells, and lymphoid and myeloid progenitors.1,2,4

  1. Stillwell R, et al. T cell signal transduction and the role of CD7 in costimulation. Immunol Res. 2001; 24:31-52.
  2. Schanberg LE, et al. Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene. Proc Natl Acad Sci USA. 1991; 88:603-7.
  3. Chabannon C, et al. Expression of CD7 on normal human myeloid progenitors. J Immunol. 1992; 149:2110-3.
  4. Rabinowich H, et al. Expression and function of CD7 molecule on human natural killer cells. J Immunol. 2003; 152: 517-26.

Specifications


  • Reactivity: paraffin
  • Visualization: membranous
  • Control: tonsil, peripheral T-cell lymphoma
  • Dilution Range: 1:100-1:500*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate107R-14
0.5 mL concentrate107R-15
1 mL concentrate107R-16
1 mL predilute107R-17
7 mL predilute107R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate107R-14
0.5 mL concentrate107R-15
1 mL concentrate107R-16
1 mL predilute107R-17
7 mL predilute107R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate107R-14
0.5 mL concentrate107R-15
1 mL concentrate107R-16
1 mL predilute107R-17
7 mL predilute107R-18

For research use only (RUO) in Japan

0.1 mL concentrate107R-14-RUO
0.5 mL concentrate107R-15-RUO
1 mL concentrate107R-16-RUO
1 mL predilute107R-17-RUO
7 mL predilute107R-18-RUO

 

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