Glucagon (EP74) Rabbit Monoclonal Antibody

Glucagon
Glucagon (EP74) on pancreatic neuroendocrine tumor.

Glucagon (EP74) Rabbit Monoclonal Antibody

Specialties: Anatomic Pathology

Updated: 2017-05-24 08:46:09

Pancreatic islets (islets of Langerhans) contain several cell types, including glucagon secreting alpha cells and insulin secreting beta cells, that work together to maintain glucose homeostasis.1-2 Glucagon is a peptide hormone that increases blood glucose through gluconeogenesis and glycogenolysis.1-3 Anti-glucagon labels glucagon secreting cells of both normal and neoplastic origin.

  1. Quesada I, et al. Physiology of the pancreatic alpha-cell and glucagon secretion: role in glucose homeostasis and diabetes. J Endocrinol. 2008; 199:5-19.
  2. Gurlo T, et al. Evaluation of immunohistochemical staining for glucagon in human pancreatic tissue. J Histotechnol. 2016; 39:8-16.
  3. Wewer Albrechtsen NJ, et al. The biology of glucagon and the consequences of hyperglucagonemia. Biomark Med. 2016; 10:1141-51.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: pancreas
  • Dilution Range: 1:100-1:200*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate259R-14
0.5 mL concentrate259R-15
1 mL concentrate259R-16
1 mL predilute259R-17
7 mL predilute259R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate259R-14
0.5 mL concentrate259R-15
1 mL concentrate259R-16
1 mL predilute259R-17
7 mL predilute259R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate259R-14
0.5 mL concentrate259R-15
1 mL concentrate259R-16
1 mL predilute259R-17
7 mL predilute259R-18

For research use only (RUO) in Japan

0.1 mL concentrate259R-14-RUO
0.5 mL concentrate259R-15-RUO
1 mL concentrate259R-16-RUO
1 mL predilute259R-17-RUO
7 mL predilute259R-18-RUO

 

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