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Stathmin (SP49)

Rabbit Monoclonal


Stathmin functions as a regulatory element in microtubule dynamics, making its role in the cell cycle critical.  Its expression is therefore ubiquitous, but it is particularly found in tissues with higher cell turnover.1-2  Stathmin expression in cervical intraepithelial neoplasia (CIN) has been demonstrated to be grade dependent, with the highest expression in CIN 3 and the least expression in CIN 1.3-4

Specialties: Breast/Gynecological Pathology Cytopathology

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: tonsil, cervical intraepithelial neoplasia-high grade
  • Isotype: IgG
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Package Inserts


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SDS

References


  1. Rubin CI. J Cell Biochem. 2004; 93:242-50.
  2. Belletti B, et al. Expert Opin Ther Targets. 2011; 15:1249-66.
  3. Syrjanen KJ. Eur J Obstet Gynecol Reprod Biol. 1996; 65:45–53.
  4. Howitt BE, et al. Am J Surg Pathol. 2013; 37:89-97.

Last updated: 2017-05-24 08:46:09

Stathmin
Stathmin antibody labels in a cytoplasmic pattern the dysplastic cervical epithelium.

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Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: tonsil, cervical intraepithelial neoplasia-high grade
  • Isotype: IgG
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

References


  1. Rubin CI. J Cell Biochem. 2004; 93:242-50.
  2. Belletti B, et al. Expert Opin Ther Targets. 2011; 15:1249-66.
  3. Syrjanen KJ. Eur J Obstet Gynecol Reprod Biol. 1996; 65:45–53.
  4. Howitt BE, et al. Am J Surg Pathol. 2013; 37:89-97.

Package Inserts

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Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate 394R-14
0.5 mL concentrate 394R-15
1 mL concentrate 394R-16
1 mL predilute 394R-17
7 mL predilute 394R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate 394R-14
0.5 mL concentrate 394R-15
1 mL concentrate 394R-16
1 mL predilute 394R-17
7 mL predilute 394R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate 394R-14
0.5 mL concentrate 394R-15
1 mL concentrate 394R-16
1 mL predilute 394R-17
7 mL predilute 394R-18

For research use only (RUO) in Japan

0.1 mL concentrate 394R-14-RUO
0.5 mL concentrate 394R-15-RUO
1 mL concentrate 394R-16-RUO
1 mL predilute 394R-17-RUO
7 mL predilute 394R-18-RUO

 

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Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: tonsil, cervical intraepithelial neoplasia-high grade
  • Isotype: IgG
  • Dilution Range: 1:25-1:100*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/Perm Red
  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

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References


  1. Rubin CI. J Cell Biochem. 2004; 93:242-50.
  2. Belletti B, et al. Expert Opin Ther Targets. 2011; 15:1249-66.
  3. Syrjanen KJ. Eur J Obstet Gynecol Reprod Biol. 1996; 65:45–53.
  4. Howitt BE, et al. Am J Surg Pathol. 2013; 37:89-97.
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