GATA1 antibody stains bone marrow megakaryocytes and erythroid precursors in a nuclear reaction.
GATA1 (4F5) Mouse Monoclonal Antibody
Specialties: Hematopathology
Updated: 2017-05-24 08:46:09
GATA-1 is a nuclear transcription factor that belongs to the family of GATA proteins, which suppresses the proliferation of megakaryocytic and erythroid precursors while promoting their differentiation. GATA1 immunohistochemical reactivity is seen in erythroid, megakaryocytic, and mast cell lineages.1,2
- Elefanty A, et al. GATA Transcription Factors Associate with a Novel Class of Nuclear Bodies in Erythroblasts and Megakaryocytes. The EMBO Journal. 1996; 15:319-33.
- Rainis L, et al. Mutations in Exon 2 of GATA1 are Early Events in Megakaryocytic Malignancies Associated with Trisomy 21. Blood. 2003; 102:981-6.
Specifications
- Reactivity: paraffin
- Visualization: nuclear
- Control: bone marrow, acute myeloid leukemia
- Dilution Range: 1:25-1:100*
Package Inserts
IFU
- IVD Rev. 2.0 (CMC41721020)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 417M-14 |
| 0.5 mL concentrate | 417M-15 |
| 1 mL concentrate | 417M-16 |
| 1 mL predilute | 417M-17 |
| 7 mL predilute | 417M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 417M-14 |
| 0.5 mL concentrate | 417M-15 |
| 1 mL concentrate | 417M-16 |
| 1 mL predilute | 417M-17 |
| 7 mL predilute | 417M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 417M-14 |
| 0.5 mL concentrate | 417M-15 |
| 1 mL concentrate | 417M-16 |
| 1 mL predilute | 417M-17 |
| 7 mL predilute | 417M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 417M-14-RUO |
| 0.5 mL concentrate | 417M-15-RUO |
| 1 mL concentrate | 417M-16-RUO |
| 1 mL predilute | 417M-17-RUO |
| 7 mL predilute | 417M-18-RUO |
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