CD19 (EP169) Rabbit Monoclonal Antibody

CD19
The germinal center cells strongly express CD19 protein in the cytoplasm.

CD19 (EP169) Rabbit Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

CD19 is present in both normal and malignant B-cells and has long been considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, mantle zone cells, and scattered cells in the interfollicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, CD19 is also expressed in immature B-cells; although recent studies have described CD19 loss in a few B-cell neoplasms.1-3

  1. Kimura M, et al. Int J Hematol. 2007; 85:41-8.
  2. Masir N, et al. Histopathology. 2006; 48:239-46.
  3. Greenberg SA, et al. Neurology. 2005; 65:1782-7.

Specifications


  • Reactivity: paraffin
  • Visualization: membranous
  • Control: tonsil
  • Dilution Range: 1:50-1:200*

Package Inserts


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Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate119R-14
0.5 mL concentrate119R-15
1 mL concentrate119R-16
1 mL predilute119R-17
7 mL predilute119R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate119R-14
0.5 mL concentrate119R-15
1 mL concentrate119R-16
1 mL predilute119R-17
7 mL predilute119R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate119R-14
0.5 mL concentrate119R-15
1 mL concentrate119R-16
1 mL predilute119R-17
7 mL predilute119R-18

For research use only (RUO) in Japan

0.1 mL concentrate119R-14-RUO
0.5 mL concentrate119R-15-RUO
1 mL concentrate119R-16-RUO
1 mL predilute119R-17-RUO
7 mL predilute119R-18-RUO

 

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