CA 19-9 (121SLE) Mouse Monoclonal Antibody

CA 19-9
Colon adenocarcinoma cells show a strong cytoplasmic reaction to the CA 19-9 protein.

CA 19-9 (121SLE) Mouse Monoclonal Antibody

Specialties: Anatomic Pathology Gastrointestinal (GI) Pathology

Updated: 2017-05-24 08:46:09

Carbohydrate Antigen 19-9 (CA19-9) is a sialylated Lewis A blood group antigen.1 It is synthesized by glycosyltransferases and has been identified as a component of gangliosides, glycoproteins and mucins.1,2 Anti-CA19-9 reacts with epithelial cells of normal pancreas, stomach, and colon as well as various adenocarcinomas, including pancreatic, gastric, and colorectal adenocarcinomas.3,4

  1. Wu E, et al. CA 19-9 and Pancreatic Cancer. Clin Adv Hematol Oncol. 2013; 11:53–5.
  2. Partyka K, et al. Diverse monoclonal antibodies against the CA 19-9 antigen show variation in binding specificity with consequences for clinical interpretation. Proteomics. 2012; 12:2212-20.
  3. Remmers N, et al. Aberrant expression of mucin core proteins and O-linked glycans associated with progression of pancreatic cancer. Clin Cancer Res. 2013; 19:1981-93.
  4. Terada T. An immunohistochemical study of primary signet-ring cell carcinoma of the stomach and colorectum: III expressions of EMA, CEA, CA19-9, CDX-2, p53, Ki-67 antigen, TTF-1, vimentin, and p63 in normal mucosa and in 42 cases. Int J Clin Exp Pathol. 2013; 6:630-8.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: colon
  • Dilution Range: 1:25-1:100*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate399M-14
0.5 mL concentrate399M-15
1 mL concentrate399M-16
1 mL predilute399M-17
7 mL predilute399M-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate399M-14
0.5 mL concentrate399M-15
1 mL concentrate399M-16
1 mL predilute399M-17
7 mL predilute399M-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate399M-14
0.5 mL concentrate399M-15
1 mL concentrate399M-16
1 mL predilute399M-17
7 mL predilute399M-18

For research use only (RUO) in Japan

0.1 mL concentrate399M-14-RUO
0.5 mL concentrate399M-15-RUO
1 mL concentrate399M-16-RUO
1 mL predilute399M-17-RUO
7 mL predilute399M-18-RUO

 

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