Colon adenocarcinoma cells show a strong cytoplasmic reaction to the CA 19-9 protein.
CA19-9 (121SLE) Mouse Monoclonal Antibody
Specialties: Anatomic Pathology Gastrointestinal (GI) Pathology
Updated: 2022-12-22 15:37:11
Carbohydrate Antigen 19-9 (CA19-9) is a sialylated Lewis A blood group antigen.1 It is synthesized by glycosyltransferases and has been identified as a component of gangliosides, glycoproteins and mucins.1,2 Anti-CA19-9 reacts with epithelial cells of normal pancreas, stomach, and colon as well as various adenocarcinomas, including pancreatic, gastric, and colorectal adenocarcinomas.3,4
- Wu E, et al. CA 19-9 and Pancreatic Cancer. Clin Adv Hematol Oncol. 2013; 11:53-5.
- Partyka K, et al. Diverse monoclonal antibodies against the CA 19-9 antigen show variation in binding specificity with consequences for clinical interpretation. Proteomics. 2012; 12:2212-20.
- Remmers N, et al. Aberrant expression of mucin core proteins and O-linked glycans associated with progression of pancreatic cancer. Clin Cancer Res. 2013; 19:1981-93.
- Terada T. An immunohistochemical study of primary signet-ring cell carcinoma of the stomach and colorectum: III expressions of EMA, CEA, CA19-9, CDX-2, p53, Ki-67 antigen, TTF-1, vimentin, and p63 in normal mucosa and in 42 cases. Int J Clin Exp Pathol. 2013; 6:630-8.
Specifications
- Reactivity: paraffin
- Control: Colon (Cytoplasmic)
- Dilution Range: 1:25-1:100 *
Package Inserts
IFU
- IVD Rev. 5.0 (CMC39921050)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 399M-14 |
| 0.5 mL concentrate | 399M-15 |
| 1.0 mL concentrate | 399M-16 |
| 1.0 mL predilute ready-to-use | 399M-17 |
| 7.0 mL predilute ready-to-use | 399M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 399M-14 |
| 0.5 mL concentrate | 399M-15 |
| 1.0 mL concentrate | 399M-16 |
| 1.0 mL predilute ready-to-use | 399M-17 |
| 7.0 mL predilute ready-to-use | 399M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 399M-14 |
| 0.5 mL concentrate | 399M-15 |
| 1.0 mL concentrate | 399M-16 |
| 1.0 mL predilute ready-to-use | 399M-17 |
| 7.0 mL predilute ready-to-use | 399M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 399M-14-RUO |
| 0.5 mL concentrate (RUO) | 399M-15-RUO |
| 1.0 mL concentrate (RUO) | 399M-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 399M-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 399M-18-RUO |
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