CD2 (EP222) Rabbit Monoclonal Antibody

CD2
Tumor cells of angioimmunoblastic T-cell lymphoma shows diffuse, strong, cytoplasmic and Golgi-like granular staining by CD2 antibody.

CD2 (EP222) Rabbit Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-26 11:41:15

CD2 is one of the earliest T-cell lineage restricted antigens to appear during T-cell differentiation and only rare CD2+ cells can be found in the bone marrow. Anti-CD2 is a pan-T-cell antigen marker. Anti-CD2 is therefore useful for the identification of virtually all normal T-lymphocytes. It is also very useful in the assessment of lymphoid malignancies as it is expressed in the majority of precursor and mature T-cell lymphomas and leukemias. As with other pan-T-cell antigens, CD2 may be aberrantly deleted in some neoplastic T-cell populations, especially peripheral T-cell lymphomas. When combined with anti-CD25, anti-CD2 may assist in the identification of systemic mastocytosis and mastocytic leukemia.1-4

  1. Aguilera NS, et al. Arch Pathol Lab Med. 2006; 130:1772-9.
  2. Barrionuevo C, et al. Appl Immunohistochem Mol Morphol. 2007; 15:38-44.
  3. Bovenschen HJ, et al. Br J Dermatol. 2005; 153:72-8.
  4. Foon KA, et al. Blood 1986; 68:1- 31.

Specifications


  • Reactivity: paraffin
  • Visualization: cytoplasmic, membranous
  • Control: tonsil
  • Dilution Range: 1:50-1:200*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate102R-14
0.5 mL concentrate102R-15
1 mL concentrate102R-16
1 mL predilute102R-17
7 mL predilute102R-18

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate102R-14
0.5 mL concentrate102R-15
1 mL concentrate102R-16
1 mL predilute102R-17
7 mL predilute102R-18

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate102R-14
0.5 mL concentrate102R-15
1 mL concentrate102R-16
1 mL predilute102R-17
7 mL predilute102R-18

For research use only (RUO) in Japan

0.1 mL concentrate102R-14-RUO
0.5 mL concentrate102R-15-RUO
1 mL concentrate102R-16-RUO
1 mL predilute102R-17-RUO
7 mL predilute102R-18-RUO

 

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