Cell Marque Portfolio

ERG (EP111)

Rabbit Monoclonal


The transcription factor erythroblastosis virus E26 transforming sequence related gene (ERG) functions as a regulator of key cellular functions to promote endothelial homeostasis.1 Expression of ERG has been observed in both benign and malignant vascular endothelial tumors, such as hemangiomas and Kaposi sarcomas, respectively.2,3 Carcinomas of the breast, colon, and urothelium have demonstrated absence of ERG expression, whereas presence of the protein has been confirmed in a subset of prostate carcinoma cases.4,5 Anti-ERG can be a useful tool for identifying vascular endothelial neoplasms and distinguishing prostate carcinoma from epithelial tumors of non-prostatic origin.

Specialties: Anatomic Pathology Genitourinary (GU) Pathology

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: hemangioma, tonsil
  • Isotype: IgG
  • Dilution Range: 1:100-1:200*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Cell Marque HiDef
    T-PC/10minAb/HiDef/Perm Red
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

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References


  1. Shah AV, et al. Vascul Pharmacol. 2016; 86:3-13.
  2. Miettinen M, et al. Am J Surg Pathol. 2011; 35:432-441.
  3. Minner S, et al. Modpathol. 2013; 26:106-116.
  4. Hornick JL. Modern Pathology. 2014; 27:S47-S63.
  5. Tomlins SA, et al. Am J Clin Pathol. 2013; 139:771-779.

Last updated: 2017-02-21 12:13:34

ERG
Prostatic acinar carcinoma is stained positive by ERG antibody in a nuclear pattern. Note on the right low grade prostate intraepithelial neoplasia is completely negative for ERG.

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Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: hemangioma, tonsil
  • Isotype: IgG
  • Dilution Range: 1:100-1:200*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Cell Marque HiDef
    T-PC/10minAb/HiDef/Perm Red
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

References


  1. Shah AV, et al. Vascul Pharmacol. 2016; 86:3-13.
  2. Miettinen M, et al. Am J Surg Pathol. 2011; 35:432-441.
  3. Minner S, et al. Modpathol. 2013; 26:106-116.
  4. Hornick JL. Modern Pathology. 2014; 27:S47-S63.
  5. Tomlins SA, et al. Am J Clin Pathol. 2013; 139:771-779.

Download an IFU

Select revision:



Ordering Information

For in vitro diagnostic (IVD) use in USA

DescriptionCat. No.
0.1 ml, concentrate 434R-14
0.5 ml, concentrate 434R-15
1 ml, concentrate 434R-16
1 ml, predilute 434R-17
7 ml, predilute 434R-18
25 ml, predilute 434R-10

For in vitro diagnostic (IVD) use in Canada

DescriptionCat. No.
0.1 ml, concentrate 434R-14
0.5 ml, concentrate 434R-15
1 ml, concentrate 434R-16
1 ml, predilute 434R-17
7 ml, predilute 434R-18
25 ml, predilute 434R-10

For in vitro diagnostic (IVD) use in the EU

DescriptionCat. No.
0.1 ml, concentrate 434R-14
0.5 ml, concentrate 434R-15
1 ml, concentrate 434R-16
1 ml, predilute 434R-17
7 ml, predilute 434R-18
25 ml, predilute 434R-10

For research use only (RUO) in Japan

DescriptionCat. No.
0.1 ml, concentrate 434R-14 (RUO)
0.5 ml, concentrate 434R-15 (RUO)
1 ml, concentrate 434R-16 (RUO)
1 ml, predilute 434R-17 (RUO)
7 ml, predilute 434R-18 (RUO)
25 ml, predilute 434R-10 (RUO)

Specifications


  • Reactivity: paraffin
  • Visualization: nuclear
  • Control: hemangioma, tonsil
  • Isotype: IgG
  • Dilution Range: 1:100-1:200*

Protocols


  • Cell Marque HiDef
    T-PC/10-30minAb/HiDef/DAB
  • Cell Marque HiDef
    T-PC/10minAb/HiDef/Perm Red
  • Ventana ultraView
    UV/CC1S/32min @ 37°C

Download an IFU

Select revision:


Keycode Specific IFU

Keycode:
Select prefix.
Please verify your keycode and try again. If problems presist contact Customer Service
Enter keycode.
Please verify your keycode and try again. If problems presist contact Customer Service

Some products may have special labeling requirements in the United States.

Are you located in the U.S.?


*Note: IFUs with the prefix RUO or ASR are only available for download in English.



Click here to learn about keycodes

References


  1. Shah AV, et al. Vascul Pharmacol. 2016; 86:3-13.
  2. Miettinen M, et al. Am J Surg Pathol. 2011; 35:432-441.
  3. Minner S, et al. Modpathol. 2013; 26:106-116.
  4. Hornick JL. Modern Pathology. 2014; 27:S47-S63.
  5. Tomlins SA, et al. Am J Clin Pathol. 2013; 139:771-779.
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