CD5 (EP77) Rabbit Monoclonal Antibody

CD5
Lymphocytes in the mantel zone (lymph node) are labelled by CD5 antibody.

CD5 (EP77) Rabbit Monoclonal Antibody

Specialties: Hematopathology

Updated: 2017-05-24 08:46:09

Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma.1,2  CD5 aberrant expression is useful in identification of mature T-cell neoplasms.3,4,5 Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23.1,3 Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies.1,6 In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.1,2

  1. Chan JKC, et al. Histopathology. 1994; 25:517-536.
  2. Jones NH, et al. Nature. 1986; 323:346-349.
  3. Tan SH, et al. Br J Dermatol. 2003; 149:542-53.
  4. Chang CC, et al. Mod Pathol. 2002; 15:1051-7.
  5. Hatano B, et al. Pathol Int. 2002; 52:400-5.
  6. West RB, et al. Am J Clin Pathol. 2002; 117:636-43.

Specifications


  • Reactivity: paraffin
  • Visualization: membranous
  • Control: tonsil, lymph node
  • Dilution Range: 1:50-1:100*

Package Inserts


IFU SDS

Ordering Information

For in vitro diagnostic (IVD) use in USA

0.1 mL concentrate205R-24
0.5 mL concentrate205R-25
1 mL concentrate205R-26
1 mL predilute205R-27
7 mL predilute205R-28

For in vitro diagnostic (IVD) use in Canada

0.1 mL concentrate205R-24
0.5 mL concentrate205R-25
1 mL concentrate205R-26
1 mL predilute205R-27
7 mL predilute205R-28

For in vitro diagnostic (IVD) use in Europe

0.1 mL concentrate205R-24
0.5 mL concentrate205R-25
1 mL concentrate205R-26
1 mL predilute205R-27
7 mL predilute205R-28

For research use only (RUO) in Japan

0.1 mL concentrate205R-24-RUO
0.5 mL concentrate205R-25-RUO
1 mL concentrate205R-26-RUO
1 mL predilute205R-27-RUO
7 mL predilute205R-28-RUO

 

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